Small cell lung cancer (SCLC) is characterized by rapid growth and high metastatic capacity.
It has strong epidemiologic and biologic links to tobacco carcinogens. Although the majority …

Radiation therapy (RT) is a curative treatment for many malignancies and provides effective
palliation in patients with tumor‐related symptoms. However, the biophysical effects of RT …

Purpose To provide guidance to clinicians regarding therapy for patients with brain
metastases from solid tumors. Methods ASCO convened an Expert Panel and conducted a …

Highlights•This Clinical Practice Guideline provides management recommendations for
patients with brain metastases from solid tumours.•The guideline covers clinical and …

Purpose This guideline provides updated evidence-based recommendations addressing
recent developments in the management of patients with brain metastases, including …

Primary lung cancer remains the most common malignancy after non-melanocytic skin
cancer, and deaths from lung cancer exceed those from any other malignancy worldwide [1] …

PURPOSE Radiation dose to the neuroregenerative zone of the hippocampus has been
found to be associated with cognitive toxicity. Hippocampal avoidance (HA) using intensity …

Brain metastases are a very common manifestation of cancer that have historically been
approached as a single disease entity given the uniform association with poor clinical …

An estimated 20% of all patients with cancer will develop brain metastases, with the majority
of brain metastases occurring in those with lung, breast and colorectal cancers, melanoma …

Background Whole brain radiotherapy (WBRT) is the standard of care to improve intracranial
control following resection of brain metastasis. However, stereotactic radiosurgery (SRS) to …