Africa is the birthplace of modern humans, and is the source of the geographic expansion of
ancestral populations into other regions of the world. Indigenous Africans are characterized …

Examining patterns of molecular genetic variation in both modern-day and ancient humans
has proved to be a powerful approach to learn about our origins. Rapid advances in DNA …

Demographic models built from genetic data play important roles in illuminating prehistorical
events and serving as null models in genome scans for selection. We introduce an inference …

In the absence of recent admixture between species, bipartitions of individuals in gene trees
that are shared across loci can potentially be used to infer the presence of two or more …

Species are commonly thought to be evolutionarily independent in a way that populations
within a species are not. In recent years, studies that seek to identify evolutionarily …

The history of click-speaking Khoe-San, and African populations in general, remains poorly
understood. We genotyped∼ 2.3 million single-nucleotide polymorphisms in 220 southern …

Protection of populations comprising admixed genomes is a challenge under the
Endangered Species Act (ESA), which is regarded as the most powerful species protection …

A long-debated question concerns the fate of archaic forms of the genus Homo: did they go
extinct without interbreeding with anatomically modern humans, or are their genes present …

Whole-genome sequencing across multiple samples in a population provides an
unprecedented opportunity for comprehensively characterizing the polymorphic variants in …

Signals of archaic admixture have been identified through comparisons of the draft
Neanderthal and Denisova genomes with those of living humans. Studies of individual loci …