Sleep is an important physiologic process, and lack of sleep is associated with a host of
adverse outcomes. Basic and clinical research has documented the important role circadian …

Rationale: Poor sleep quality is common in the intensive care unit (ICU) and may be
associated with adverse outcomes. Hence, ICU-based efforts to promote sleep are gaining …

Objective: To update and expand the 2013 Clinical Practice Guidelines for the Management
of Pain, Agitation, and Delirium in Adult Patients in the ICU. Design:

Rationale: Dexmedetomidine is associated with less delirium than benzodiazepines and
better sleep architecture than either benzodiazepines or propofol; its effect on delirium and …

Background: Sleep and circadian disruption (SCD) is common and severe in the ICU. On the
basis of rigorous evidence in non-ICU populations and emerging evidence in ICU …

Abstract Study Objectives Sleep is reflected not only in the electroencephalogram but also in
heart rhythms and breathing patterns. We hypothesized that it is possible to accurately stage …

Background Delirium is a deleterious condition affecting up to 60% of patients in the surgical
ICU (SICU). Few SICU-focused delirium interventions have been implemented, including …

Objectives: Circadian rhythms are severely disrupted among the critically ill. These circadian
arrhythmias impair mentation, immunity, autonomic function, endocrine activity, hormonal …

Abstract Purpose of Review Poor sleep and delirium are common in older patients but
recognition and management are challenging, particularly in the intensive care unit (ICU) …

Objective: This study aimed to assess whether interventions targeted at improving sleep in
the ICU were associated with reductions in ICU delirium. Secondary outcomes include …