Iron recycling prevents the development of anemia under homeostatic conditions. Whether
iron recycling was co-opted as a defense strategy to prevent the development of anemia in …

Malaria and iron deficiency are major global health problems with extensive epidemiological
overlap. Iron deficiency-induced anaemia can protect the host from malaria by limiting …

Genetic mapping has been widely employed to search for genes linked to phenotypes/traits
of interest. Because of the ease of maintaining rodent malaria parasites in laboratory mice …

Hypoglycemia is a clinical hallmark of severe malaria, the often-lethal outcome of
Plasmodium falciparum infection. Here, we report that malaria-associated hypoglycemia …

Rodent malaria parasites (RMPs) allow the study of malaria parasite biology across its entire
life cycle through a vertebrate host and a mosquito vector under laboratory conditions …

CD4+ αβ T-cells are key mediators of the immune response to a first Plasmodium infection,
undergoing extensive activation and splenic expansion during the acute phase of an …

Abstract Background Rodent malaria parasites (RMPs) serve as tractable tools to study
malaria parasite biology and host-parasite-vector interactions. Among the four RMPs …

Bulk RNA sequencing of Plasmodium spp., the causative parasite of malaria, fails to
discriminate developmental-stage-specific gene regulation. Here, we provide a protocol that …

Background: Gastrointestinal symptoms are commonly associated with acute Plasmodium
spp infection. Malaria-associated enteritis may provide an opportunity for enteric pathogens …

Iron deficiency and malaria are two major public health problems with largely overlapping
epidemiology, and there is a complex relationship between iron and malaria. Iron deficiency …