Phenotypes in pulmonary hypertension

J Weatherald, AR Hemnes, BA Maron… - European …, 2024 - publications.ersnet.org
The clinical classification of pulmonary hypertension (PH) has guided diagnosis and
treatment of patients with PH for several decades. Discoveries relating to underlying …

Therapeutic augmentation of NO-sGC-cGMP signalling: lessons learned from pulmonary arterial hypertension and heart failure

F Triposkiadis, A Xanthopoulos, J Skoularigis… - Heart failure …, 2022 - Springer
The nitric oxide (NO)–guanylate cyclase (GC)–cyclic guanosine monophosphate (cGMP)
pathway plays an important role in cardiovascular, pulmonary and renal function …

Differentiating precapillary from postcapillary pulmonary hypertension: pulmonary artery wedge pressure versus left ventricular end-diastolic pressure

R Naeije, K Chin - Circulation, 2019 - Am Heart Assoc
Beyond the interchangeability between end-diastolic PAWP and LVEDP, another common
question is whether measurements should be averaged over the respiratory cycle. The heart …

Bedside assessment of left atrial pressure in critical care: a multifaceted gem

EM Bowcock, A Mclean - Critical Care, 2022 - Springer
Evaluating left atrial pressure (LAP) solely from the left ventricular preload perspective is a
restrained approach. Accurate assessment of LAP is particularly relevant when pulmonary …

Impact of the new pulmonary hypertension definition on heart transplant outcomes: expanding the hemodynamic risk profile

TC Crawford, PJ Leary, CD Fraser III, A Suarez-Pierre… - Chest, 2020 - Elsevier
Background At the recent 6th World Symposium on Pulmonary Hypertension (PH), the
definition of PH was redefined to include lower pulmonary artery pressures in the setting of …

Pulmonary Arterial hypertension in the elderly: peculiar features and challenges for a proper phenotyping approach

R Scagliola, C Brunelli, M Balbi - Journal of Cardiovascular Development …, 2023 - mdpi.com
(1) Introduction. Although pulmonary arterial hypertension (PAH) usually affects young
people with a low cardiovascular risk profile, progressive epidemiologic changes have been …

A fluid challenge test for the diagnosis of occult heart failure

M d'Alto, D Badesch, E Bossone, BA Borlaug, E Brittain… - Chest, 2021 - Elsevier
A right heart catheterization with measurements of pulmonary artery wedge pressure
(PAWP) may be necessary for the diagnosis of left heart failure as a cause of pulmonary …

Modern right heart catheterization: beyond simple hemodynamics

EL Bonno, MC Viray, GR Jackson… - Advances in …, 2020 - meridian.allenpress.com
Preparation is the key to success. Even before entering the catheterization lab, the operator
should have a suspicion of what will be found on the hemodynamic evaluation. Do the …

Circulating NEDD9 is increased in pulmonary arterial hypertension: a multicenter, retrospective analysis

AO Samokhin, S Hsu, BY Paul, AB Waxman… - The Journal of Heart and …, 2020 - Elsevier
BACKGROUND Pulmonary arterial hypertension (PAH) is a highly morbid disease
characterized by elevated pulmonary vascular resistance (PVR) and pathogenic right …

[HTML][HTML] Left ventricle unloading during veno-arterial extracorporeal membrane oxygenation: review with updated evidence

Y Lim, MC Kim, IS Jeong - Acute and Critical Care, 2024 - synapse.koreamed.org
Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is widely used to treat
medically refractory cardiogenic shock and cardiac arrest, and its usage has increased …