[HTML][HTML] SYNCAS: Efficient CRISPR/Cas9 gene-editing in difficult to transform arthropods
The genome editing technique CRISPR/Cas9 has led to major advancements in many
research fields and this state-of-the-art tool has proven its use in genetic studies for various …
research fields and this state-of-the-art tool has proven its use in genetic studies for various …
Biotechnology-enhanced genetic controls of the global pest Drosophila suzukii
Y Yan, HMM Ahmed, EA Wimmer, MF Schetelig - Trends in Biotechnology, 2024 - cell.com
Abstract Spotted wing Drosophila (Drosophila suzukii Matsumura, or SWD), an insect pest of
soft-skinned fruits native to East Asia, has rapidly spread worldwide in the past 15 years …
soft-skinned fruits native to East Asia, has rapidly spread worldwide in the past 15 years …
Gene drive and genetic sex conversion in the global agricultural pest Ceratitis capitata
A Meccariello, S Hou, S Davydova, JD Fawcett… - Nature …, 2024 - nature.com
Homing-based gene drives are recently proposed interventions promising the area-wide,
species-specific genetic control of harmful insect populations. Here we characterise a first …
species-specific genetic control of harmful insect populations. Here we characterise a first …
AY chromosome-linked genome editor for efficient population suppression in the malaria vector Anopheles gambiae
Genetic control–the deliberate introduction of genetic traits to control a pest or vector
population–offers a powerful tool to augment conventional mosquito control tools that have …
population–offers a powerful tool to augment conventional mosquito control tools that have …
Developing genetic tools to control the Oriental fruit fly: Potential approaches and target genes
Abstract The Oriental fruit fly, Bactrocera dorsalis, is a pest of significant economic interest
that damages horticulture and causes major economic losses worldwide. The main control …
that damages horticulture and causes major economic losses worldwide. The main control …
Population suppression by release of insects carrying a dominant sterile homing gene drive targeting doublesex in Drosophila
W Chen, J Guo, Y Liu, J Champer - Nature Communications, 2024 - nature.com
CRISPR homing gene drives can suppress pest populations by targeting female fertility
genes, converting wild-type alleles into drive alleles in the germline of drive heterozygotes …
genes, converting wild-type alleles into drive alleles in the germline of drive heterozygotes …
Improving the suppressive power of homing gene drive by co-targeting a distant-site female fertility gene
Gene drive technology has the potential to address major biological challenges. Well-
studied homing suppression drives have been shown to be highly efficient in Anopheles …
studied homing suppression drives have been shown to be highly efficient in Anopheles …
[HTML][HTML] SYNCAS based CRISPR-Cas9 gene editing in predatory mites, whiteflies and stinkbugs
A Mocchetti, S De Rouck, S Naessens… - Insect Biochemistry and …, 2025 - Elsevier
Despite the establishment of CRISPR-Cas9 gene editing protocols in a wide range of
organisms, genetic engineering is still challenging for many organisms due to constraints …
organisms, genetic engineering is still challenging for many organisms due to constraints …
Population suppression with dominant female-lethal alleles is boosted by homing gene drive
Background Methods to suppress pest insect populations using genetic constructs and
repeated releases of male homozygotes have recently been shown to be an attractive …
repeated releases of male homozygotes have recently been shown to be an attractive …
Germline Cas9 promoters with improved performance for homing gene drive
J Du, W Chen, X Jia, X Xu, E Yang, R Zhou… - Nature …, 2024 - nature.com
Gene drive systems could be a viable strategy to prevent pathogen transmission or suppress
vector populations by propagating drive alleles with super-Mendelian inheritance. CRISPR …
vector populations by propagating drive alleles with super-Mendelian inheritance. CRISPR …