The ketone bodies acetoacetate (AcAc) and β-hydroxybutyrate (βHB) have pleiotropic
effects in multiple organs including brain, heart, and skeletal muscle by serving as an …

The development of mobile and wearable sensing devices for continuous ketone detection
has received tremendous recent attention. These devices have opened the doors to …

There is a need to optimize closed-loop automated insulin delivery in type 1 diabetes. We
assessed the glycemic efficacy and safety of empagliflozin 25 mg d− 1 as add-on therapy to …

The American Diabetes Association (ADA), European Association for the Study of Diabetes
(EASD), Joint British Diabetes Societies for Inpatient Care (JBDS), American Association of …

Diabetic ketoacidosis (DKA) is a life-threatening complication, which is most common in
individuals with type 1 diabetes (T1D) and is a significant risk for morbidity and mortality, and …

Abstract The American Diabetes Association (ADA), European Association for the Study of
Diabetes (EASD), Joint British Diabetes Societies for Inpatient Care (JBDS), American …

OBJECTIVE To assess whether low doses of empagliflozin as adjunct to hybrid closed-loop
therapy improve glycemia compared with placebo in adults with type 1 diabetes (T1D) who …

Ketone bodies are an energy substrate produced by the liver and used during states of low
carbohydrate availability, such as fasting or prolonged exercise. High ketone concentrations …

For 25 years, continuous glucose monitoring (CGM) has been evolving into what it is now: a
key tool to both measure individuals' glycemic status and to help guide their day-to-day …

Exogenous oral ketone supplements, primarily in form of ketone salts or esters, have
emerged as a useful research tool for manipulating metabolism with potential therapeutic …