Helicobacter pylori is the first formally recognized bacterial carcinogen and is one of the
most successful human pathogens, as over half of the world's population is colonized with …

Glutathione transferases (GST) catalyze the conjugation of glutathione (GSH) with
electrophiles, many of which may otherwise interact with protein or DNA. In select cases …

Risk factors for gastric cancer (GC) include inter-individual variability in the inflammatory
response to Helicobacter pylori infection, in the ability of detoxifying DNA reactive species …

The input into the QIVIVE and Physiologically-Based kinetic and dynamic models of drug
metabolising enzymes performance and their inter-individual differences significantly …

The association between glutathione S‐transferase T1 (GSTT1) polymorphism and gastric
cancer risk has been both confirmed and refuted in a number of published studies. Most of …

Gastric cancer has been recognized as an important cause of morbidity and mortality all
over the world. Helicobacter pylori has been shown to have a causal relationship to gastric …

OBJECTIVE: The objective of the study was to evaluate the influence of genetic
polymorphisms of GSTM1, GSTT1, and GSTM3 on the susceptibility of cervical cancer …

Abstract Preterm delivery (PTD,< 37 weeks of gestation) is a significant clinical and public
health problem. Previously, we reported that maternal smoking and metabolic gene …

Introduction: Glutathione S-transferases (GSTs) are considered to be cancer susceptibility
genes as they play a role in the detoxification of carcinogenic species. This study aimed to …

Human glutathione S-transferases (GSTs) are phase II metabolizing enzymes that play a key
role in protecting against cancer by detoxifying numerous potentially cytotoxic/genotoxic …