Flaviviruses are emerging and re-emerging arthropod-borne pathogens responsible for
significant mortality and morbidity worldwide. The genus comprises more than seventy …

Japanese encephalitis virus (JEV) is a flavivirus, spread by the bite of carrier Culex
mosquitoes. The subsequent disease caused is Japanese encephalitis (JE), which is the …

Having appropriate in vivo and in vitro systems that provide translational models for human
disease is an integral aspect of research in neurobiology and the neurosciences. Traditional …

Membrane rafts are dynamic, small (10–200 nm) domains enriched with cholesterol and
sphingolipids that compartmentalize cellular processes. Rafts participate in roles essential to …

The Flavivirus genus consists of> 70 members including several that are considered
significant human pathogens. Flaviviruses display a broad spectrum of diseases that can be …

Highlights•Flavivirus replication occurs on modified ER membranes called vesicle packets
(Vp) and membrane vesicles (Ve).•Flavivirus non-structural proteins are implicated in …

Parkinsonism secondary to viral infections is not an uncommon occurrence and has been
brought under the spotlight with the spread of severe acute respiratory syndrome …

Neurotropic RNA viruses continue to emerge and are increasingly linked to diseases of the
central nervous system (CNS) despite viral clearance. Indeed, the overall mortality of viral …

Japanese encephalitis virus (JEV), a mosquito-borne flavivirus, is the leading cause of viral
encephalitis in Southeast Asia with potential to become a global pathogen. Here, we identify …

Flaviviruses are emerging arthropod-borne pathogens that cause life-threatening diseases
such as yellow fever, dengue, West Nile encephalitis, tick-borne encephalitis, Kyasanur …