Outbreaks of severe virus infections with the potential to cause global pandemics are
increasing. In many instances these outbreaks have been newly emerging (SARS …

SUMMARY West Nile Virus was introduced into the Western Hemisphere during the late
summer of 1999 and has been causing significant and sometimes severe human diseases …

Flaviviruses, such as the dengue virus and the West Nile virus, are emerging arthropod-
borne viruses that represent an immense global health problem. Considerable progress has …

Arthropod-borne viruses (arboviruses) pose a significant threat to global health, causing
human disease with increasing geographic range and severity. The recent availability of the …

Japanese encephalitis virus (JEV) is an arbovirus belonging to the family Flaviviridae. It is
maintained in a zoonotic cycle involving pigs, ardeid birds and Culex species of mosquitoes …

Infections with viruses in the genus Flavivirus are a worldwide public health problem. These
enveloped, positive sense single stranded RNA viruses use a small complement of only 10 …

The ability of many viruses to manipulate the host antiviral immune response often results in
complex host-pathogen interactions. In order to study the interaction of dengue virus (DENV) …

A decade has passed since the appearance of West Nile virus (WNV) in humans in the
Western Hemisphere in New York City. During this interval, WNV spread inexorably …

Genome-wide investigations of host–pathogen interactions are often limited by analyses of
mixed populations of infected and uninfected cells, which lower sensitivity and accuracy. To …

The genus Flavivirus contains approximately 70 arthropod-borne enveloped RNA viruses
many of which cause severe human and in some cases, animal disease. They include …