[HTML][HTML] Determinants and outcomes of mitochondrial dynamics

R Quintana-Cabrera, L Scorrano - Molecular Cell, 2023 - cell.com
Mitochondria are not only central organelles in metabolism and energy conversion but are
also platforms for cellular signaling cascades. Classically, the shape and ultrastructure of …

[HTML][HTML] Mitochondrial dysfunction and oxidative stress in Alzheimer's disease

A Misrani, S Tabassum, L Yang - Frontiers in aging neuroscience, 2021 - frontiersin.org
Mitochondria play a pivotal role in bioenergetics and respiratory functions, which are
essential for the numerous biochemical processes underpinning cell viability. Mitochondrial …

Mitochondrial dynamics and its involvement in disease

DC Chan - Annual review of pathology: mechanisms of disease, 2020 - annualreviews.org
The dynamic properties of mitochondria—including their fusion, fission, and degradation—
are critical for their optimal function in energy generation. The interplay of fusion and fission …

Mitochondrial fusion: the machineries in and out

S Gao, J Hu - Trends in cell biology, 2021 - cell.com
Mitochondria are highly dynamic organelles that constantly undergo fission and fusion.
Disruption of mitochondrial dynamics undermines their function and causes several human …

Mitochondrial dynamics: overview of molecular mechanisms

L Tilokani, S Nagashima, V Paupe… - Essays in …, 2018 - portlandpress.com
Mitochondria are highly dynamic organelles undergoing coordinated cycles of fission and
fusion, referred as 'mitochondrial dynamics', in order to maintain their shape, distribution and …

Mitochondrial dynamics in health and disease

NMB Yapa, V Lisnyak, B Reljic, MT Ryan - FEBS letters, 2021 - Wiley Online Library
In animals, mitochondria are mainly organised into an interconnected tubular network
extending across the cell along a cytoskeletal scaffold. Mitochondrial fission and fusion, as …

Endoplasmic reticulum–mitochondrial contactology: structure and signaling functions

G Csordás, D Weaver, G Hajnóczky - Trends in cell biology, 2018 - cell.com
Interorganellar contacts are increasingly recognized as central to the control of cellular
behavior. These contacts, which typically involve a small fraction of the endomembrane …

Molecular mechanisms of coronary microvascular endothelial dysfunction in diabetes mellitus: focus on mitochondrial quality surveillance

D Sun, J Wang, S Toan, D Muid, R Li, X Chang, H Zhou - Angiogenesis, 2022 - Springer
Coronary microvascular endothelial dysfunction is both a culprit and a victim of diabetes,
and can accelerate diabetes-related microvascular and macrovascular complications by …

[HTML][HTML] Mitochondrial fission and fusion: A dynamic role in aging and potential target for age-related disease

YJ Liu, RL McIntyre, GE Janssens… - Mechanisms of ageing …, 2020 - Elsevier
The mitochondria is the major hub to convert energy for cellular processes. Dysregulation of
mitochondrial function is one of the classical hallmarks of aging, and mitochondrial …

Nrf2 as a regulator of mitochondrial function: Energy metabolism and beyond

N Esteras, AY Abramov - Free Radical Biology and Medicine, 2022 - Elsevier
Mitochondria are unique and essential organelles that mediate many vital cellular processes
including energy metabolism and cell death. The transcription factor Nrf2 (NF-E2 p45 …