Histone variants at a glance
PB Talbert, S Henikoff - Journal of Cell Science, 2021 - journals.biologists.com
Eukaryotic nucleosomes organize chromatin by wrapping 147 bp of DNA around a histone
core particle comprising two molecules each of histone H2A, H2B, H3 and H4. The DNA …
core particle comprising two molecules each of histone H2A, H2B, H3 and H4. The DNA …
Histone variants—ancient wrap artists of the epigenome
PB Talbert, S Henikoff - Nature reviews Molecular cell biology, 2010 - nature.com
Histones wrap DNA to form nucleosome particles that compact eukaryotic genomes. Variant
histones have evolved crucial roles in chromosome segregation, transcriptional regulation …
histones have evolved crucial roles in chromosome segregation, transcriptional regulation …
Essential role of histone replacement and modifications in male fertility
Spermiogenesis is a complex cellular differentiation process that the germ cells undergo a
distinct morphological change, and the protamines replace the core histones to facilitate …
distinct morphological change, and the protamines replace the core histones to facilitate …
Paternal DNA packaging in spermatozoa: more than the sum of its parts? DNA, histones, protamines and epigenetics
D Miller, M Brinkworth, D Iles - Reproduction, 2010 - rep.bioscientifica.com
Testicular tumours in dogs are of Sertoli cell, Leydig cell or germinal origin and mixed
tumours are also frequently observed. The cellular components of mixed tumours are …
tumours are also frequently observed. The cellular components of mixed tumours are …
Function of sperm chromatin structural elements in fertilization and development
WS Ward - MHR: Basic science of reproductive medicine, 2009 - academic.oup.com
Understanding how DNA is packaged in the mammalian sperm cell has important
implications for human infertility as well as for the cell biology. Recent advances in the study …
implications for human infertility as well as for the cell biology. Recent advances in the study …
[HTML][HTML] Epigenetics of the male gamete
DT Carrell - Fertility and sterility, 2012 - Elsevier
OBJECTIVE: To review and summarize the current understanding of the epigenetic status of
human sperm in regards to protamination, specific localization and modifications of retained …
human sperm in regards to protamination, specific localization and modifications of retained …
Altered protamine expression and diminished spermatogenesis: what is the link?
DT Carrell, BR Emery… - Human reproduction …, 2007 - academic.oup.com
During the elongating spermatid stage of spermiogenesis, human sperm chromatin
undergoes a complex transition in which histones are extensively replaced by protamines in …
undergoes a complex transition in which histones are extensively replaced by protamines in …
Histone variants meet their match
K Sarma, D Reinberg - Nature reviews Molecular cell biology, 2005 - nature.com
A fascinating aspect of how chromatin structure impacts on gene expression and cellular
identity is the transmission of information from mother to daughter cells, independently of the …
identity is the transmission of information from mother to daughter cells, independently of the …
[HTML][HTML] Pericentric heterochromatin reprogramming by new histone variants during mouse spermiogenesis
J Govin, E Escoffier, S Rousseaux, L Kuhn… - The Journal of cell …, 2007 - ncbi.nlm.nih.gov
During male germ cell postmeiotic maturation, dramatic chromatin reorganization occurs,
which is driven by completely unknown mechanisms. For the first time, we describe a …
which is driven by completely unknown mechanisms. For the first time, we describe a …
Structural basis of instability of the nucleosome containing a testis-specific histone variant, human H3T
H Tachiwana, W Kagawa, A Osakabe… - Proceedings of the …, 2010 - National Acad Sciences
A histone H3 variant, H3T, is highly expressed in the testis, suggesting that it may play an
important role in the chromatin reorganization required for meiosis and/or spermatogenesis …
important role in the chromatin reorganization required for meiosis and/or spermatogenesis …