Cigarette smoking (CS) can impact the immune system and induce pulmonary disorders
such as chronic obstructive pulmonary disease (COPD), which is currently the fourth leading …

There is considerable evidence that matrix metalloproteinases (MMPs) are up-and/or
downregulated in chronic obstructive pulmonary disease (COPD), particularly in …

Cytokines play an important part in many pathobiological processes of chronic obstructive
pulmonary disease (COPD), including the chronic inflammatory process, emphysema, and …

Chronic obstructive pulmonary disease (COPD) is characterized by airflow obstruction that
results from an inflammatory process affecting the airways and lung parenchyma. Despite …

The beneficial properties of the pineal hormone, melatonin, as a neuroprotective and
cardioprotective agent, have been previously identified. Furthermore, melatonin plays …

Pulmonary hypertension is a prevalent complication of chronic obstructive pulmonary
disease (COPD) that is associated with poor prognosis. Although pulmonary hypertension is …

Pulmonary vascular remodeling is an angiogenic-related process involving changes in
smooth muscle cell (SMC) homeostasis, which is frequently observed in chronic obstructive …

Cigarette smoke has a crucial impact on transcriptome alteration by its effect on chromatin
remodeling and DNA methylation status. The first mechanism is associated with the histone …

Oxidative stress driven by several environmental and local airway factors associated with
chronic obstructive bronchiolitis, a hallmark feature of COPD, plays a crucial role in disease …

Introduction The RNA-binding protein AU-rich-element factor-1 (AUF-1) participates to
posttranscriptional regulation of genes involved in inflammation and cellular senescence …