Angiogenesis, the formation of new blood vessels, is a complex and dynamic process
regulated by various pro-and anti-angiogenic molecules, which plays a crucial role in tumor …

Significance: Proangiogenic therapy appeared a promising strategy for the treatment of
patients with acute myocardial infarction (MI), as de novo formation of microvessels, has the …

Background—We investigated the therapeutic potential of ex vivo expanded endothelial
progenitor cells (EPCs) for myocardial neovascularization. Methods and Results …

Human mesenchymal stem cells (MSCs) are increasingly being considered in cell‐based
therapeutic strategies for regeneration of various organs/tissues. However, the signals …

Background—Administration of cardiac progenitor cells (CPCs) 4 hours after reperfusion
ameliorates left ventricular function in rats with acute myocardial infarction (MI). Clinically …

During the past decade, emerging evidence has accumulated of different nuclear
transcription factors in regulation of cardiac development and growth as well as in cardiac …

Using a rat model of ischemia/reperfusion injury, we demonstrate here that HGF is
cardioprotective due to its antiapoptotic effect on cardiomyocytes. Following transient …

Besides mediating primary hemostasis and thrombosis, platelets play a critical role in tissue
repair and regeneration. They regulate fundamental mechanisms involved in the healing …

Background—Scatter factor/hepatocyte growth factor (SF/HGF) is a pleiotropic growth factor
that stimulates proliferation and migration of endothelial cells (ECs) via the c-Met receptor …

Background—Adult stem cells can contribute to myocardial regeneration after ischemic
injury. Bone marrow and skeletal muscles contain a population of CXCR4+ cells expressing …