Strengthening the immune system and reducing inflammation and oxidative stress through diet and nutrition: considerations during the COVID-19 crisis

M Iddir, A Brito, G Dingeo, SS Fernandez Del Campo… - Nutrients, 2020 - mdpi.com
The coronavirus-disease 2019 (COVID-19) was announced as a global pandemic by the
World Health Organization. Challenges arise concerning how to optimally support the …

The role of vitamin E in immunity

GY Lee, SN Han - Nutrients, 2018 - mdpi.com
Vitamin E is a fat-soluble antioxidant that can protect the polyunsaturated fatty acids (PUFAs)
in the membrane from oxidation, regulate the production of reactive oxygen species (ROS) …

Nutritional modulation of immune function: analysis of evidence, mechanisms, and clinical relevance

D Wu, ED Lewis, M Pae, SN Meydani - Frontiers in immunology, 2019 - frontiersin.org
It is well-established that the nutritional deficiency or inadequacy can impair immune
functions. Growing evidence suggests that for certain nutrients increased intake above …

Regulatory role of vitamin E in the immune system and inflammation

ED Lewis, SN Meydani, D Wu - IUBMB life, 2019 - Wiley Online Library
Vitamin E, a potent lipid‐soluble antioxidant, found in higher concentration in immune cells
compared to other cells in blood, is one of the most effective nutrients known to modulate …

Aging and immune function: molecular mechanisms to interventions

S Ponnappan, U Ponnappan - 2011 - liebertpub.com
The immune system of an organism is an essential component of the defense mechanism
aimed at combating pathogenic stress. Age-associated immune dysfunction, also dubbed …

Cytokine storm in aged people with CoV-2: possible role of vitamins as therapy or preventive strategy

S Fiorino, C Gallo, M Zippi, S Sabbatani… - Aging clinical and …, 2020 - Springer
Abstract Background In December 2019, a novel human-infecting coronavirus, SARS-CoV-
2, had emerged. The WHO has classified the epidemic as a “public health emergency of …

Non-antioxidant activities of vitamin E

JM Zingg, A Azzi - Current medicinal chemistry, 2004 - ingentaconnect.com
Molecules in biological systems often can perform more than one function. In particular,
many molecules have the ability to chemically scavenge free radicals and thus act in the test …

The role of nutrition in enhancing immunity in aging

M Pae, SN Meydani, D Wu - Aging and disease, 2011 - pmc.ncbi.nlm.nih.gov
Aging is associated with declined immune function, particularly T cell-mediated activity,
which contributes to increased morbidity and mortality from infectious disease and cancer in …

Antigen sparing and cross-reactive immunity with an adjuvanted rH5N1 prototype pandemic influenza vaccine: a randomised controlled trial

I Leroux-Roels, A Borkowski, T Vanwolleghem… - The Lancet, 2007 - thelancet.com
Background Antigen sparing is regarded as crucial for pandemic vaccine development
because worldwide influenza vaccine production capacity is limited. Adjuvantation is an …

Type 2 diabetes mellitus and inflammation: Prospects for biomarkers of risk and nutritional intervention

A Badawi, A Klip, P Haddad, DEC Cole… - … syndrome and obesity …, 2010 - Taylor & Francis
Obesity is a major risk factor for type 2 diabetes mellitus (T2DM), which is a significant health
problem worldwide. Active disease is associated with low-grade chronic inflammation …