[HTML][HTML] A review of sarcopenia pathophysiology, diagnosis, treatment and future direction
MR Cho, S Lee, SK Song - Journal of Korean medical …, 2022 - synapse.koreamed.org
Sarcopenia is a progressive and generalized loss of skeletal muscle mass and function. The
prevalence of sarcopenia was reported to be up to 29% in older persons in the community …
prevalence of sarcopenia was reported to be up to 29% in older persons in the community …
Role of the nervous system in sarcopenia and muscle atrophy with aging: strength training as a countermeasure
P Aagaard, C Suetta, P Caserotti… - … journal of medicine …, 2010 - Wiley Online Library
Aging is characterized by loss of spinal motor neurons (MNs) due to apoptosis, reduced
insulin‐like growth factor I signaling, elevated amounts of circulating cytokines, and …
insulin‐like growth factor I signaling, elevated amounts of circulating cytokines, and …
Exercise-induced autophagy suppresses sarcopenia through Akt/mTOR and Akt/FoxO3a signal pathways and AMPK-mediated mitochondrial quality control
Z Zeng, J Liang, L Wu, H Zhang, J Lv… - Frontiers in physiology, 2020 - frontiersin.org
Exercise training is one of the most effective interventional strategies for sarcopenia in aged
people. Nevertheless, the underlying mechanisms are not well recognized. Increasing …
people. Nevertheless, the underlying mechanisms are not well recognized. Increasing …
[HTML][HTML] Sarcopenia: its assessment, etiology, pathogenesis, consequences and future perspectives
Y Rolland, S Czerwinski, GA Van Kan, JE Morley… - The Journal of nutrition …, 2008 - Elsevier
Sarcopenia is a loss of muscle protein mass and loss of muscle function. It occurs with
increasing age, being a major component in the development of frailty. Current knowledge …
increasing age, being a major component in the development of frailty. Current knowledge …
Role of age-related mitochondrial dysfunction in sarcopenia
Skeletal muscle aging is associated with a significant loss of skeletal muscle strength and
power (ie, dynapenia), muscle mass and quality of life, a phenomenon known as …
power (ie, dynapenia), muscle mass and quality of life, a phenomenon known as …
Machine learning on human muscle transcriptomic data for biomarker discovery and tissue-specific drug target identification
For the past several decades, research in understanding the molecular basis of human
muscle aging has progressed significantly. However, the development of accessible tissue …
muscle aging has progressed significantly. However, the development of accessible tissue …
Cellular and molecular mechanisms underlying age-related skeletal muscle wasting and weakness
JG Ryall, JD Schertzer, GS Lynch - Biogerontology, 2008 - Springer
Some of the most serious consequences of ageing are its effects on skeletal muscle. The
term 'sarcopenia'describes the slow but progressive loss of muscle mass with advancing …
term 'sarcopenia'describes the slow but progressive loss of muscle mass with advancing …
Effects of aging on human skeletal muscle after immobilization and retraining
C Suetta, LG Hvid, L Justesen… - Journal of applied …, 2009 - journals.physiology.org
Inactivity is a recognized compounding factor in sarcopenia and muscle weakness in old
age. However, while the negative effects of unloading on skeletal muscle in young …
age. However, while the negative effects of unloading on skeletal muscle in young …
New horizons in the pathogenesis, diagnosis and management of sarcopenia
Sarcopenia is the age-related loss of skeletal muscle mass and function. It is now
recognised as a major clinical problem for older people and research in the area is …
recognised as a major clinical problem for older people and research in the area is …
Denervation causes fiber atrophy and myosin heavy chain co-expression in senescent skeletal muscle
Although denervation has long been implicated in aging muscle, the degree to which it is
causes the fiber atrophy seen in aging muscle is unknown. To address this question, we …
causes the fiber atrophy seen in aging muscle is unknown. To address this question, we …