The concept of an epigenetic landscape describing potential cellular fates arising from
pluripotent cells, first advanced by Conrad Waddington, has evolved in light of experiments …

Importance Gastroesophageal reflux disease (GERD) is defined by recurrent and
troublesome heartburn and regurgitation or GERD-specific complications and affects …

Importance Long-term results from randomized clinical trials comparing laparoscopic sleeve
gastrectomy (LSG) with laparoscopic Roux-en-Y-gastric bypass (LRYGB) are limited …

Importance The Patient Health Questionnaire depression module (PHQ-9) is a 9-item self-
administered instrument used for detecting depression and assessing severity of …

During cancer progression, tumor cells undergo molecular and phenotypic changes
collectively referred to as cellular plasticity. Such changes result from microenvironmental …

The 5-year survival rate in esophageal cancer, although poor, has improved over the past
decade. This review discusses the epidemiologic aspects, pathogenesis, prevention, and …

Anorexia nervosa and bulimia nervosa are serious psychiatric illnesses related to
disordered eating and distorted body images. They both have significant medical …

Metaplasia is the replacement of one differentiated somatic cell type with another
differentiated somatic cell type in the same tissue. Typically, metaplasia is triggered by …

Epithelial cells line the entire surface of the gastrointestinal tract and its accessory organs
where they primarily function in transporting digestive enzymes, nutrients, electrolytes, and …

Oesophageal cancer is a clinically challenging disease that requires a multidisciplinary
approach. Extensive treatment might be associated with a considerable decline in health …