Mechanism of action, resistance, synergism, and clinical implications of azithromycin

M Heidary, A Ebrahimi Samangani… - Journal of clinical …, 2022 - Wiley Online Library
Background Azithromycin (AZM), sold under the name Zithromax, is classified as a
macrolide. It has many benefits due to its immunomodulatory, anti‐inflammatory, and …

Biocompatible materials in otorhinolaryngology and their antibacterial properties

J Spałek, P Ociepa, P Deptuła, E Piktel… - International Journal of …, 2022 - mdpi.com
For decades, biomaterials have been commonly used in medicine for the replacement of
human body tissue, precise drug-delivery systems, or as parts of medical devices that are …

[HTML][HTML] Medical device-associated infections caused by biofilm-forming microbial pathogens and controlling strategies

A Mishra, A Aggarwal, F Khan - Antibiotics, 2024 - mdpi.com
Hospital-acquired infections, also known as nosocomial infections, include bloodstream
infections, surgical site infections, skin and soft tissue infections, respiratory tract infections …

Long-term, low-dose macrolide antibiotic treatment in pediatric chronic airway diseases

J Sun, Y Li - Pediatric research, 2022 - nature.com
Macrolide antibiotics are one of the most commonly used broad-spectrum antibiotics. They
have an inhibitory effect on a variety of respiratory pathogens; besides, they have non-anti …

Advances in Antimicrobial Coatings for Preventing Infections of Head-Related Implantable Medical Devices

I Negut, C Albu, B Bita - Coatings, 2024 - mdpi.com
During surgery and after, pathogens can contaminate indwelling and implanted medical
devices, resulting in serious infections. Microbial colonization, infection, and later biofilm …

Chitosan-coated azithromycin/ciprofloxacin-loaded polycaprolactone nanoparticles: a characterization and potency study

AE Yassin, AM Albekairy, ME Omer… - Nanotechnology …, 2023 - Taylor & Francis
Purpose Antimicrobial resistance is a major health hazard worldwide. Combining
azithromycin (AZ) and ciprofloxacin (CIP) in one drug delivery system was proposed to boost …

Clinical Efficacy and In Vitro Drug Sensitivity Test Results of Azithromycin Combined With Other Antimicrobial Therapies in the Treatment of MDR P. aeruginosa …

Y Huang, W Wang, Q Huang, Z Wang, Z Xu… - Frontiers in …, 2022 - frontiersin.org
Objective: The aim of the research was to study the effect of azithromycin (AZM) in the
treatment of MDR P. aeruginosa VAP combined with other antimicrobial therapies. Methods …

Novel strategies for inhibition of bacterial biofilm in chronic rhinosinusitis

A Shariati, S Vesal, A Khoshbayan… - Journal of Applied …, 2022 - academic.oup.com
An important role has been recently reported for bacterial biofilm in the pathophysiology of
chronic diseases, such as chronic rhinosinusitis (CRS). CRS, affecting sinonasal mucosa, is …

The mechanism of action and clinical efficacy of low-dose long-term macrolide therapy in chronic rhinosinusitis

G Ryu, E Lee, SI Park, M Park, SD Hong… - International Journal of …, 2023 - mdpi.com
Various chronic inflammatory airway diseases can be treated with low-dose, long-term
(LDLT) macrolide therapy. LDLT macrolides can be one of the therapeutic options for …

Azithromycin and ciprofloxacin inhibit interleukin‐8 secretion without disrupting human sinonasal epithelial integrity in vitro

DJ Lim, HM Thompson, CR Walz… - International forum of …, 2021 - Wiley Online Library
Background We recently developed a ciprofloxacin and azithromycin sinus stent (CASS) to
target recalcitrant infections in chronic rhinosinusitis (CRS). The objective of this study was …