There are still major challenges regarding the early diagnosis and treatment of chronic
kidney disease (CKD), which is in part due to the fact that its pathophysiology is very …

Heart failure (HF) and chronic kidney disease (CKD) co-exist, and it is estimated that about
50% of HF patients suffer from CKD. Although studies have been performed on the …

Chronic kidney disease (CKD) promotes development of cardiac abnormalities and is highly
prevalent in patients with heart failure, particularly in those with preserved ejection fraction …

Chronic kidney disease is a global health problem affecting 10% to 12% of the population.
Uremic cardiomyopathy is often characterized by left ventricular hypertrophy, fibrosis, and …

Diabetic cardiomyopathy (CM), occurring in the absence of hypertension, coronary artery
disease, and valvular or congenital heart disease, is now recognized as a distinct …

The high prevalence of cardiovascular disease in patients with chronic kidney disease
indicates significant interactions between pathogenic pathways operating in the kidney and …

Uremic Cardiomyopathy (UCM) is an irreversible cardiovascular complication that is highly
pervasive among chronic kidney disease (CKD) patients, particularly in End-Stage Kidney …

Prediabetes is a condition affecting more than 35% of the population. In some forms,
excessive carbohydrate intake (primarily refined sugar) plays a prominent role. Prediabetes …

Heart failure with preserved ejection fraction (HFpEF) is the largest unmet clinical need in
cardiovascular medicine. Despite decades of research, the treatment option for HFpEF is still …

Radiation-induced heart disease (RIHD) is a potential late side-effect of thoracic
radiotherapy resulting in left ventricular hypertrophy (LVH) and fibrosis due to a complex …