1001 lights: luciferins, luciferases, their mechanisms of action and applications in chemical analysis, biology and medicine

ZM Kaskova, AS Tsarkova, IV Yampolsky - Chemical Society Reviews, 2016 - pubs.rsc.org
Bioluminescence (BL) is a spectacular phenomenon involving light emission by live
organisms. It is caused by the oxidation of a small organic molecule, luciferin, with molecular …

Clinical imaging in regenerative medicine

AV Naumova, M Modo, A Moore, CE Murry… - Nature …, 2014 - nature.com
In regenerative medicine, clinical imaging is indispensable for characterizing damaged
tissue and for measuring the safety and efficacy of therapy. However, the ability to track the …

Sequential and sustained release of SDF-1 and BMP-2 from silk fibroin-nanohydroxyapatite scaffold for the enhancement of bone regeneration

X Shen, Y Zhang, Y Gu, Y Xu, Y Liu, B Li, L Chen - Biomaterials, 2016 - Elsevier
In this study, a cell-free bone tissue engineering system based on a silk fibroin (SF)/nano-
hydroxyapatite (nHAp) scaffold was developed, in which two bioactive molecules, stromal …

Injectable hydrogels with in situ double network formation enhance retention of transplanted stem cells

L Cai, RE Dewi, SC Heilshorn - Advanced functional materials, 2015 - Wiley Online Library
Stem cell transplantation via direct injection is a minimally invasive strategy being explored
for treatment of a variety of injuries and diseases. Injectable hydrogels with shear moduli< …

[HTML][HTML] Chemiluminescence and bioluminescence imaging for biosensing and therapy: in vitro and in vivo perspectives

Y Yan, P Shi, W Song, S Bi - Theranostics, 2019 - ncbi.nlm.nih.gov
Chemiluminescence (CL) and bioluminescence (BL) imaging technologies, which require
no external light source so as to avoid the photobleaching, background interference and …

In vivo cell tracking with bioluminescence imaging

JE Kim, S Kalimuthu, BC Ahn - Nuclear Medicine and Molecular Imaging, 2015 - Springer
Molecular imaging is a fast growing biomedical research that allows the visual
representation, characterization and quantification of biological processes at the cellular and …

Transplantation and tracking of human-induced pluripotent stem cells in a pig model of myocardial infarction: assessment of cell survival, engraftment, and distribution …

C Templin, R Zweigerdt, K Schwanke, R Olmer… - Circulation, 2012 - Am Heart Assoc
Background—Evaluation of novel cellular therapies in large-animal models and patients is
currently hampered by the lack of imaging approaches that allow for long-term monitoring of …

Concise review: workshop review: understanding and assessing the risks of stem cell-based therapies

JA Heslop, TG Hammond, I Santeramo… - Stem cells …, 2015 - academic.oup.com
The field of stem cell therapeutics is moving ever closer to widespread application in the
clinic. However, despite the undoubted potential held by these therapies, the balance …

Intra-articular delivery of purified mesenchymal stem cells from C57BL/6 or MRL/MpJ superhealer mice prevents posttraumatic arthritis

BO Diekman, CL Wu, CR Louer… - Cell …, 2013 - journals.sagepub.com
Joint injury dramatically enhances the onset of osteoarthritis (OA) and is responsible for an
estimated 12% of OA. Posttraumatic arthritis (PTA) is especially common after intra-articular …

[HTML][HTML] Protein-engineered injectable hydrogel to improve retention of transplanted adipose-derived stem cells

A Parisi-Amon, W Mulyasasmita, C Chung… - Advanced healthcare …, 2013 - ncbi.nlm.nih.gov
Improved retention of transplanted stem cells is achieved through minimally invasive
delivery in MITCH, a Mixing-Induced Two-Component Hydrogel engineered to possess …