Cellular exposure to ionizing radiation leads to oxidizing events that alter atomic structure
through direct interactions of radiation with target macromolecules or via products of water …

The current concept of radiobiology posits that damage to the DNA in the cell nucleus is the
primary cause for the detrimental effects of radiation. However, emerging experimental …

Non-targeted effects (NTE) have been generally regarded as a low-dose ionizing radiation
(IR) phenomenon. Recently, regarding long distant abscopal effects have also been …

Radiation therapy is one of the pillars of cancer treatment, with approximately one half of all
cancer patients receiving it as part of their standard of care. Emerging evidence indicates …

Significance: Ionizing radiation is a vital component in the oncologist's arsenal for the
treatment of cancer. Approximately 50% of all cancer patients will receive some form of …

Not-targeted effects represent a paradigm shift from the “DNA centric” view that ionizing
radiation only elicits biological effects and subsequent health consequences as a result of …

Accidental exposure to ionizing radiation is a serious concern to human life. Studies on the
mitigation of side effects following exposure to accidental radiation events are ongoing …

Mitochondria-nuclear coadaptation has been central to eukaryotic evolution. The dynamic
dialogue between the two compartments within the context of multiorganellar interactions is …

A spectrum of radiation-induced non-targeted effects has been reported during the last two
decades since Nagasawa and Little first described a phenomenon in cultured cells that was …

Bystander or non-targeted effect is known to be an interesting phenomenon in radiobiology.
The genetic consequences of bystander effect on non-irradiated cells have shown that this …