Metabolomics for clinical use and research in chronic kidney disease

B Hocher, J Adamski - Nature Reviews Nephrology, 2017 - nature.com
Chronic kidney disease (CKD) has a high prevalence in the general population and is
associated with high mortality; a need therefore exists for better biomarkers for diagnosis …

How could metabolomics change pediatric health?

F Bardanzellu, V Fanos - Italian Journal of Pediatrics, 2020 - Springer
In the last years,'omics' technologies, and especially metabolomics, emerged as expanding
scientific disciplines and promising technologies in the characterization of several …

Urinary 1H-NMR and GC-MS metabolomics predicts early and late onset neonatal sepsis

V Fanos, P Caboni, G Corsello, M Stronati… - Early human …, 2014 - Elsevier
The purpose of this article is to study one of the most significant causes of neonatal morbidity
and mortality: neonatal sepsis. This pathology is due to a bacterial or fungal infection …

Bacille Calmette-Guérin vaccine reprograms human neonatal lipid metabolism in vivo and in vitro

J Diray-Arce, A Angelidou, KJ Jensen, MG Conti… - Cell reports, 2022 - cell.com
Vaccines have generally been developed with limited insight into their molecular impact.
While systems vaccinology enables characterization of mechanisms of action, these tools …

Urinary metabolomics of bronchopulmonary dysplasia (BPD): preliminary data at birth suggest it is a congenital disease

V Fanos, M Cristina Pintus, M Lussu… - The Journal of …, 2014 - Taylor & Francis
Objective: Bronchopulmonary dysplasia (BPD) or chronic lung disease is one of the
principal causes of mortality and morbidity in preterm infants. Early identification of infants at …

Metabolomics in retinal diseases: an update

X Li, S Cai, Z He, J Reilly, Z Zeng, N Strang, X Shu - Biology, 2021 - mdpi.com
Simple Summary Visual loss and blindness caused by retinal disease has a significant
negative effect on the quality of life of many adults and children, and as a result has become …

Metabolomics in pharmacology-a delve into the novel field of pharmacometabolomics

M Mussap, C Loddo, C Fanni… - Expert review of clinical …, 2020 - Taylor & Francis
Introduction: Pharmacometabolomics is an emerging science pursuing the application of
precision medicine. Combining both genetic and environmental factors, the so-called …

Evolution of newborns' urinary metabolomic profiles according to age and growth

A Scalabre, E Jobard, D Demede… - Journal of Proteome …, 2017 - ACS Publications
Improving the management of neonatal diseases and prevention of chronic diseases in
adulthood requires a better comprehension of the complex maturational processes …

Lipidomics—Paving the Road towards Better Insight and Precision Medicine in Rare Metabolic Diseases

M Zandl-Lang, B Plecko, H Köfeler - International Journal of Molecular …, 2023 - mdpi.com
Even though the application of Next-Generation Sequencing (NGS) has significantly
facilitated the identification of disease-associated mutations, the diagnostic rate of rare …

Next‐Generation Technologies for Multiomics Approaches Including Interactome Sequencing

H Ohashi, M Hasegawa, K Wakimoto… - BioMed research …, 2015 - Wiley Online Library
The development of high‐speed analytical techniques such as next‐generation sequencing
and microarrays allows high‐throughput analysis of biological information at a low cost …