Revealing the effect of skull deformation on intracranial pressure variation during the direct interaction between blast wave and surrogate head

Z Du, Z Li, P Wang, X Wang, J Zhang, Z Zhuang… - Annals of Biomedical …, 2022 - Springer
Intracranial pressure (ICP) during the interaction between blast wave and the head is a
crucial evaluation criterion for blast-induced traumatic brain injury (bTBI). ICP variation is …

A finite rotation, small strain 2D elastic head model, with applications in mild traumatic brain injury

Y Wan, W Fang, RW Carlsen, H Kesari - … of the Mechanics and Physics of …, 2023 - Elsevier
Rotational head motions have been shown to play a key role in traumatic brain injury. There
is great interest in developing methods to rapidly predict brain tissue strains and strain rates …

Acceleration effect on stress singularity and edge strength in piezoelectric/Piezomagnetic heterostructures

Y Guo, L Hua, J Wang, J Du, B Huang - Applied Mathematical Modelling, 2025 - Elsevier
The acceleration effect on edge stress singularity and edge strength in piezoelectric/
piezomagnetic heterostructures is investigated in this work. For the stress singularity …

Cortical spheroids show strain-dependent cell viability loss and neurite disruption following sustained compression injury

RD González-Cruz, Y Wan, A Burgess, D Calvao… - Plos one, 2024 - journals.plos.org
Sustained compressive injury (SCI) in the brain is observed in numerous injury and
pathological scenarios, including tumors, ischemic stroke, and traumatic brain injury-related …

Theoretical and numerical analysis for angular acceleration being determinant of brain strain in mTBI

Y Liu, X Zhan, AG Domel, M Fanton, Z Zhou… - arXiv preprint arXiv …, 2020 - arxiv.org
Mild traumatic brain injury (mTBI, also known as concussion) caused by the head impact is a
crucial global public health problem, but the physics of mTBI is still unclear. During the …

A mechanics theory for the exploration of a high-throughput, sterile 3D in vitro traumatic brain injury model

Y Wan, RD González-Cruz, D Hoffman-Kim… - … and modeling in …, 2024 - Springer
Brain injuries resulting from mechanical trauma represent an ongoing global public health
issue. Several in vitro and in vivo models for traumatic brain injury (TBI) continue to be …

Determining rigid body motion from accelerometer data through the square-root of a negative semi-definite tensor, with applications in mild traumatic brain injury

Y Wan, AL Fawzi, H Kesari - Computer Methods in Applied Mechanics and …, 2022 - Elsevier
Abstract Mild Traumatic Brain Injuries (mTBI) are caused by violent head motions or impacts.
Most mTBI prevention strategies explicitly or implicitly rely on a “brain injury criterion”. A …

Sawtooth patterns in flexural force curves of structural biological materials are not signatures of toughness enhancement: Part I

S Kochiyama, W Fang, MA Monn, H Kesari - Journal of the Mechanical …, 2021 - Elsevier
Layered architectures are prevalent in tough biological composites, such as nacre and
bone. Another example of a biological composite with layered architecture is the skeletal …

Functional significance of lamellar architecture in marine sponge fibers: Conditions for when splitting a cylindrical tube into an assembly of tubes will decrease its …

S Kochiyama, BE Grossman-Ponemon… - Journal of the Mechanics …, 2023 - Elsevier
Numerous ingenious engineering designs and devices have been the product of bio-
inspiration. Bone, nacre, and other such stiff structural biological materials (SSBMs) are …

A mechanics theory for the exploration of a high-throughput, sterile 3D traumatic brain injury model

Y Wan, RD González-Cruz, D Hoffman-Kim… - arXiv preprint arXiv …, 2023 - arxiv.org
Brain injuries resulting from mechanical trauma represent an ongoing global public health
issue. Several $\textit {in vitro} $ and $\textit {in vivo} $ models for traumatic brain injury (TBI) …