The'silent epidemic'of traumatic brain injury (TBI) has been placed in the spotlight as a result
of clinical investigations and popular press coverage of athletes and veterans with single or …

ABSTRACT A long-standing goal of spinal cord injury research is to develop effective spinal
cord repair strategies for the clinic. Rat models of spinal cord injury provide an important …

Inflammatory reaction following a spinal cord injury (SCI) contributes substantially to
secondary effects, with both beneficial and devastating effects. This review summarizes the …

The Rho signaling pathway regulates the cytoskeleton and motility and plays an important
role in neuronal growth inhibition. Here we demonstrate that inactivation of Rho or its …

Recent immunohistological and imaging studies emphasize the crucial role of axonal injury
in determining the extent of permanent neurological deficits in patients with multiple …

Microglia are the main immune cells in the brain, playing a role in both physiological and
pathological conditions. Microglial involvement in neurodegenerative diseases is well …

Microglia, the standby cells for immune defense in the CNS, have a reputation for
exacerbating the neural damage that occurs in neurodegenerative diseases. However …

Transplanted neural stem/precursor cells possess peculiar therapeutic plasticity and can
simultaneously instruct several therapeutic mechanisms in addition to cell replacement …

The role of systemic autoimmunity in human traumatic brain injury (TBI) and other forms of
brain injuries is recognized but not well understood. In this study, a systematic investigation …

Multiple Sclerosis (MS) is an inflammatory demyelinating disorder of central nervous system
(CNS). Polyphenol curcumin has been used in traditional medicine as an effective drug for a …