[HTML][HTML] Novel targets, treatments, and advanced models for intracerebral haemorrhage
Intracerebral haemorrhage (ICH) is the second most common type of stroke and a major
cause of mortality and disability worldwide. Despite advances in surgical interventions and …
cause of mortality and disability worldwide. Despite advances in surgical interventions and …
[HTML][HTML] Microglia at the blood brain barrier in health and disease
MG Mayer, T Fischer - Frontiers in Cellular Neuroscience, 2024 - frontiersin.org
The blood brain barrier (BBB) plays a crucial role in maintaining brain homeostasis by
selectively preventing the entry of substances from the peripheral blood into the central …
selectively preventing the entry of substances from the peripheral blood into the central …
The stress hyperglycemia ratio predicts early hematoma expansion and poor outcomes in patients with spontaneous intracerebral hemorrhage
H Chu, C Huang, Y Tang, Q Dong… - Therapeutic Advances …, 2022 - journals.sagepub.com
Background: Different from diabetic hyperglycemia, stress-induced hyperglycemia (SIH) can
better reflect elevated blood glucose owing to intracerebral hemorrhage (ICH). However …
better reflect elevated blood glucose owing to intracerebral hemorrhage (ICH). However …
[HTML][HTML] DL-3-n-butylphthalide (NBP) alleviates poststroke cognitive impairment (PSCI) by suppressing neuroinflammation and oxidative stress
H Zhang, L Wang, Y Yang, C Cai, X Wang… - Frontiers in …, 2023 - frontiersin.org
Currently, the recovery of cognitive function has become an essential part of stroke
rehabilitation. DL-3-n-butylphthalide (NBP) is a neuroprotective reagent and has been used …
rehabilitation. DL-3-n-butylphthalide (NBP) is a neuroprotective reagent and has been used …
Associations between vascular risk factor levels and cognitive decline among Stroke survivors
DA Levine, B Chen, AT Galecki, AL Gross… - JAMA network …, 2023 - jamanetwork.com
Importance Incident stroke is associated with accelerated cognitive decline. Whether
poststroke vascular risk factor levels are associated with faster cognitive decline is uncertain …
poststroke vascular risk factor levels are associated with faster cognitive decline is uncertain …
3-N-butylphthalide attenuates neuroinflammation in rotenone-induced Parkinson's disease models via the cGAS-STING pathway
Y Liu, R Duan, P Li, B Zhang… - International Journal of …, 2024 - journals.sagepub.com
Neuroinflammation is crucial in the onset and progression of dopaminergic neuron loss in
Parkinson's disease (PD). We aimed to determine whether 3-N-Butylphthalide (NBP) can …
Parkinson's disease (PD). We aimed to determine whether 3-N-Butylphthalide (NBP) can …
The ER chaperone, BIP protects Microglia from ER stress-mediated Apoptosis in Hyperglycemia
AW James, GA Bahader, M Albassan… - Neurochemistry …, 2023 - Elsevier
A major endoplasmic reticulum (ER) chaperone, binding of Immunoglobulin heavy chain
protein (BIP) facilitates the assembly of newly synthesized proteins in the ER. Microglia …
protein (BIP) facilitates the assembly of newly synthesized proteins in the ER. Microglia …
Neurobehavioral and inflammatory responses following traumatic brain injury in male and female mice
Traumatic brain injury (TBI) is a leading cause of mortality and is associated with a high rate
of functional comorbidities, including motor, cognitive, anxiety, depression, and emotional …
of functional comorbidities, including motor, cognitive, anxiety, depression, and emotional …
[HTML][HTML] Swimming training mitigates neurological impairment of intracerebral haemorrhage in mice via the serine-threonine kinase/glycogen synthase kinase 3β …
Y Li, T Lu, W Wei, Z Lin, L Ding, Z Li, X Xue - Neuroscience, 2022 - Elsevier
Swimming training (ST) can mitigate functional disorders in neurological diseases, but the
effect and mechanism of ST in improving the neurological function of intracerebral …
effect and mechanism of ST in improving the neurological function of intracerebral …
[HTML][HTML] Rodent models of post-stroke dementia
Post-stroke cognitive impairment is one of the most common complications in stroke
survivors. Concomitant vascular risk factors, including aging, diabetes mellitus …
survivors. Concomitant vascular risk factors, including aging, diabetes mellitus …