[HTML][HTML] Leishmania infections: Molecular targets and diagnosis
Progress in the diagnosis of leishmaniases depends on the development of effective
methods and the discovery of suitable biomarkers. We propose firstly an update …
methods and the discovery of suitable biomarkers. We propose firstly an update …
[HTML][HTML] Drug repurposing and human parasitic protozoan diseases
Parasitic diseases have an enormous health, social and economic impact and are a
particular problem in tropical regions of the world. Diseases caused by protozoa and …
particular problem in tropical regions of the world. Diseases caused by protozoa and …
Proteasome inhibition for treatment of leishmaniasis, Chagas disease and sleeping sickness
S Khare, AS Nagle, A Biggart, YH Lai, F Liang… - Nature, 2016 - nature.com
Chagas disease, leishmaniasis and sleeping sickness affect 20 million people worldwide
and lead to more than 50,000 deaths annually. The diseases are caused by infection with …
and lead to more than 50,000 deaths annually. The diseases are caused by infection with …
TriTrypDB: a functional genomic resource for the Trypanosomatidae
M Aslett, C Aurrecoechea, M Berriman… - Nucleic acids …, 2010 - academic.oup.com
ABSTRACT TriTrypDB (http://tritrypdb. org) is an integrated database providing access to
genome-scale datasets for kinetoplastid parasites, and supporting a variety of complex …
genome-scale datasets for kinetoplastid parasites, and supporting a variety of complex …
Shape, form, function and Leishmania pathogenicity: from textbook descriptions to biological understanding
J Sunter, K Gull - Open biology, 2017 - royalsocietypublishing.org
The shape and form of protozoan parasites are inextricably linked to their pathogenicity. The
evolutionary pressure associated with establishing and maintaining an infection and …
evolutionary pressure associated with establishing and maintaining an infection and …
Leishmania development in sand flies: parasite-vector interactions overview
A Dostálová, P Volf - Parasites & vectors, 2012 - Springer
Leishmaniases are vector-borne parasitic diseases with 0.9–1.4 million new human cases
each year worldwide. In the vectorial part of the life-cycle, Leishmania development is …
each year worldwide. In the vectorial part of the life-cycle, Leishmania development is …
Visceral leishmaniasis: what are the needs for diagnosis, treatment and control?
Visceral leishmaniasis (VL) is a systemic protozoan disease that is transmitted by
phlebotomine sandflies. Poor and neglected populations in East Africa and the Indian sub …
phlebotomine sandflies. Poor and neglected populations in East Africa and the Indian sub …
Cutaneous leishmaniasis
R Reithinger, JC Dujardin, H Louzir… - The Lancet infectious …, 2007 - thelancet.com
Cutaneous leishmaniasis is endemic in the tropics and neotropics. It is often referred to as a
group of diseases because of the varied spectrum of clinical manifestations, which range …
group of diseases because of the varied spectrum of clinical manifestations, which range …
Advances in leishmaniasis
HW Murray, JD Berman, CR Davies, NG Saravia - The Lancet, 2005 - thelancet.com
Governed by parasite and host factors and immunoinflammatory responses, the clinical
spectrum of leishmaniasis encompasses subclinical (inapparent), localised (skin lesions) …
spectrum of leishmaniasis encompasses subclinical (inapparent), localised (skin lesions) …
Chromosome and gene copy number variation allow major structural change between species and strains of Leishmania
MB Rogers, JD Hilley, NJ Dickens, J Wilkes… - Genome …, 2011 - genome.cshlp.org
Leishmania parasites cause a spectrum of clinical pathology in humans ranging from
disfiguring cutaneous lesions to fatal visceral leishmaniasis. We have generated a reference …
disfiguring cutaneous lesions to fatal visceral leishmaniasis. We have generated a reference …