The openCARP simulation environment for cardiac electrophysiology
Abstract Background and Objective: Cardiac electrophysiology is a medical specialty with a
long and rich tradition of computational modeling. Nevertheless, no community standard for …
long and rich tradition of computational modeling. Nevertheless, no community standard for …
A review of healthy and fibrotic myocardium microstructure modeling and corresponding intracardiac electrograms
Computational simulations of cardiac electrophysiology provide detailed information on the
depolarization phenomena at different spatial and temporal scales. With the development of …
depolarization phenomena at different spatial and temporal scales. With the development of …
Personalized ablation vs. conventional ablation strategies to terminate atrial fibrillation and prevent recurrence
Aims The long-term success rate of ablation therapy is still sub-optimal in patients with
persistent atrial fibrillation (AF), mostly due to arrhythmia recurrence originating from …
persistent atrial fibrillation (AF), mostly due to arrhythmia recurrence originating from …
Comparison of various late gadolinium enhancement magnetic resonance imaging methods with high-definition voltage and activation mapping for detection of atrial …
M Eichenlaub, B Mueller-Edenborn, J Minners… - EP …, 2022 - academic.oup.com
Aims Atrial cardiomyopathy (ACM) is associated with increased arrhythmia recurrence rates
after pulmonary vein isolation (PVI). We compare the most common left atrial (LA) late …
after pulmonary vein isolation (PVI). We compare the most common left atrial (LA) late …
Non-invasive and quantitative estimation of left atrial fibrosis based on P waves of the 12-Lead ECG—a large-scale computational study covering anatomical …
The arrhythmogenesis of atrial fibrillation is associated with the presence of fibrotic atrial
tissue. Not only fibrosis but also physiological anatomical variability of the atria and the …
tissue. Not only fibrosis but also physiological anatomical variability of the atria and the …
Fibrotic remodeling during persistent atrial fibrillation: In silico investigation of the role of calcium for human atrial myofibroblast electrophysiology
During atrial fibrillation, cardiac tissue undergoes different remodeling processes at different
scales from the molecular level to the tissue level. One central player that contributes to both …
scales from the molecular level to the tissue level. One central player that contributes to both …
Differences in atrial substrate localization using late gadolinium enhancement-magnetic resonance imaging, electrogram voltage, and conduction velocity: a cohort …
D Nairn, M Eichenlaub, B Mueller-Edenborn… - Europace, 2023 - academic.oup.com
Aims Electro-anatomical voltage, conduction velocity (CV) mapping, and late gadolinium
enhancement (LGE) magnetic resonance imaging (MRI) have been correlated with atrial …
enhancement (LGE) magnetic resonance imaging (MRI) have been correlated with atrial …
Comparison of unipolar and bipolar voltage mapping for localization of left atrial arrhythmogenic substrate in patients with atrial fibrillation
D Nairn, H Lehrmann, B Müller-Edenborn… - Frontiers in …, 2020 - frontiersin.org
Background: Presence of left atrial low voltage substrate in bipolar voltage mapping is
associated with increased arrhythmia recurrences following pulmonary vein isolation for …
associated with increased arrhythmia recurrences following pulmonary vein isolation for …
Using Machine Learning to Characterize Atrial Fibrotic Substrate From Intracardiac Signals With a Hybrid in silico and in vivo Dataset
J Sánchez, G Luongo, M Nothstein, LA Unger… - Frontiers in …, 2021 - frontiersin.org
In patients with atrial fibrillation, intracardiac electrogram signal amplitude is known to
decrease with increased structural tissue remodeling, referred to as fibrosis. In addition to …
decrease with increased structural tissue remodeling, referred to as fibrosis. In addition to …
Modeling the functional heterogeneity and conditions for the occurrence of microreentry in procedurally created atrial fibrous tissue
A Kalinin, V Naumov, S Kovalenko… - Journal of Applied …, 2023 - pubs.aip.org
The occurrence of atrial fibrillation (AF), one of the most socially significant arrhythmias, is
associated with the presence of areas of fibrosis. Fibrosis introduces conduction …
associated with the presence of areas of fibrosis. Fibrosis introduces conduction …