Oxidants in physiological processes
UG Knaus - Reactive oxygen species: Network pharmacology and …, 2021 - Springer
A number of diseases and conditions have been associated with prolonged or persistent
exposure to non-physiological levels of reactive oxygen species (ROS). Similarly, ROS …
exposure to non-physiological levels of reactive oxygen species (ROS). Similarly, ROS …
The dual role of reactive oxygen species-generating nicotinamide adenine dinucleotide phosphate oxidases in gastrointestinal inflammation and therapeutic …
PMC Dang, L Rolas, J El-Benna - Antioxidants & redox signaling, 2020 - liebertpub.com
Significance: Despite their intrinsic cytotoxic properties, mounting evidence indicates that
reactive oxygen species (ROS) physiologically produced by the nicotinamide adenine …
reactive oxygen species (ROS) physiologically produced by the nicotinamide adenine …
DUOX2 variants associate with preclinical disturbances in microbiota-immune homeostasis and increased inflammatory bowel disease risk
H Grasberger, AT Magis, E Sheng… - The Journal of …, 2021 - Am Soc Clin Investig
A primordial gut-epithelial innate defense response is the release of hydrogen peroxide by
dual NADPH oxidase (DUOX). In inflammatory bowel disease (IBD), a condition …
dual NADPH oxidase (DUOX). In inflammatory bowel disease (IBD), a condition …
[HTML][HTML] Biomarkers prediction and immune landscape in ulcerative colitis: Findings based on bioinformatics and machine learning
Y Yang, Y Hua, H Zheng, R Jia, Z Ye, G Su, Y Gu… - Computers in Biology …, 2024 - Elsevier
Background Ulcerative colitis (UC) presents diagnostic and therapeutic difficulties. The
primary objective of this study is to identify efficacious biomarkers for diagnosis and …
primary objective of this study is to identify efficacious biomarkers for diagnosis and …
Guidelines for newborn screening of congenital hypothyroidism (2021 revision)
K Nagasaki, K Minamitani, A Nakamura… - Clinical Pediatric …, 2023 - jstage.jst.go.jp
Purpose of developing the guidelines: Newborn screening (NBS) for congenital
hypothyroidism (CH) was started in 1979 in Japan, and early diagnosis and treatment …
hypothyroidism (CH) was started in 1979 in Japan, and early diagnosis and treatment …
Novel biallelic mutations in the DUOX2 gene underlying very early-onset inflammatory bowel disease: A case report
Genetic variants affecting the function of dual oxidase 2 (DUOX2), the catalytic subunit of
membrane-bound enzymes that produce hydrogen peroxide, are associated with very early …
membrane-bound enzymes that produce hydrogen peroxide, are associated with very early …
DUOX defects and their roles in congenital hypothyroidism
X De Deken, F Miot - NADPH Oxidases: Methods and Protocols, 2019 - Springer
Extracellular hydrogen peroxide is required for thyroperoxidase-mediated thyroid hormone
synthesis in the follicular lumen of the thyroid gland. Among the NADPH oxidases, dual …
synthesis in the follicular lumen of the thyroid gland. Among the NADPH oxidases, dual …
Incidence and predictors of new persistent opioid use following inflammatory bowel disease flares treated with oral corticosteroids
M Noureldin, PDR Higgins, SM Govani… - Alimentary …, 2019 - Wiley Online Library
Background Opioids are commonly prescribed to manage pain associated with inflammatory
bowel disease (IBD). It is unknown what percentage of patients develop new persistent …
bowel disease (IBD). It is unknown what percentage of patients develop new persistent …
NADPH oxidases in inflammatory bowel disease
E Stenke, B Bourke, UG Knaus - NADPH oxidases: methods and protocols, 2019 - Springer
Inflammatory bowel diseases (IBD), categorized as ulcerative colitis (UC), Crohn's disease
(CD), or IBD-undetermined (IBDU), are increasing in incidence. IBD is understood to result …
(CD), or IBD-undetermined (IBDU), are increasing in incidence. IBD is understood to result …
Intestinal IL-17R signaling controls secretory IgA and oxidase balance in Citrobacter rodentium infection
Y Matsunaga, T Clark, AG Wanek, JP Bitoun… - The Journal of …, 2021 - journals.aai.org
Type 17 cytokines have been strongly implicated in mucosal immunity, in part by regulating
the production of antimicrobial peptides. Using a mouse model of Citrobacter rodentium …
the production of antimicrobial peptides. Using a mouse model of Citrobacter rodentium …