Background When the original definition of BOS was formulated in 1993, the working group
had several goals. The group aimed to provide a classification system for airway disease …

Over the last decade, improvements in surgical techniques, lung preservation,
immunosuppression, and management of ischemia–reperfusion injury and infections have …

Bronchiolitis obliterans syndrome (BOS) is a major complication of lung transplantation that
is associated with poor survival. The International Society for Heart and Lung …

BACKGROUND: Aspiration of gastroesophageal refluxate may contribute to lung transplant
bronchiolitis obliterans syndrome (BOS). We investigated bile acids in bronchoalveolar …

Bronchiolitis obliterans syndrome remains the leading cause of morbidity and mortality in the
pulmonary transplant population. Previous studies show that macrolide antibiotics may be …

Rationale: Bronchiolitis obliterans syndrome (BOS) remains the leading cause of death after
lung transplantation. Treatment is difficult, although azithromycin has recently been shown to …

Background We conducted a placebo-controlled trial of azithromycin therapy in bronchiolitis
obliterans syndrome (BOS) post lung transplantation. Methods We compared azithromycin …

Increased levels of the neutrophil chemokine interleukin (IL)-8 in the lungs of severe trauma
patients can predict subsequent development of acute respiratory distress syndrome …

Chronic lung allograft dysfunction (CLAD) is the major limitation of long-term survival after
lung transplantation. Chronic lung allograft dysfunction manifests as bronchiolitis obliterans …

Bronchiolitis obliterans syndrome (BOS) is the major limitation to survival after lung
transplantation. Acute rejection, its main risk factor, is characterized by perivascular …