Meiotic recombination: the essence of heredity

N Hunter - Cold Spring Harbor perspectives in biology, 2015 - cshperspectives.cshlp.org
The study of homologous recombination has its historical roots in meiosis. In this context,
recombination occurs as a programmed event that culminates in the formation of crossovers …

The molecular biology of meiosis in plants

R Mercier, C Mézard, E Jenczewski… - Annual review of …, 2015 - annualreviews.org
Meiosis is the cell division that reshuffles genetic information between generations.
Recently, much progress has been made in understanding this process; in particular, the …

The genetic and epigenetic landscape of the Arabidopsis centromeres

M Naish, M Alonge, P Wlodzimierz, AJ Tock… - Science, 2021 - science.org
INTRODUCTION The centromeres of eukaryotic chromosomes assemble the multiprotein
kinetochore complex and thereby position attachment to the spindle microtubules, allowing …

SyRI: finding genomic rearrangements and local sequence differences from whole-genome assemblies

M Goel, H Sun, WB Jiao, K Schneeberger - Genome biology, 2019 - Springer
Genomic differences range from single nucleotide differences to complex structural
variations. Current methods typically annotate sequence differences ranging from SNPs to …

Cycles of satellite and transposon evolution in Arabidopsis centromeres

P Wlodzimierz, FA Rabanal, R Burns, M Naish… - Nature, 2023 - nature.com
Centromeres are critical for cell division, loading CENH3 or CENPA histone variant
nucleosomes, directing kinetochore formation and allowing chromosome segregation …

Brassica carinata genome characterization clarifies U's triangle model of evolution and polyploidy in Brassica

X Song, Y Wei, D Xiao, K Gong, P Sun, Y Ren… - Plant …, 2021 - academic.oup.com
Ethiopian mustard (Brassica carinata) in the Brassicaceae family possesses many excellent
agronomic traits. Here, the high-quality genome sequence of B. carinata is reported …

Stable recombination hotspots in birds

S Singhal, EM Leffler, K Sannareddy, I Turner, O Venn… - Science, 2015 - science.org
The DNA-binding protein PRDM9 has a critical role in specifying meiotic recombination
hotspots in mice and apes, but it appears to be absent from other vertebrate species …

Meiotic recombination: mixing it up in plants

Y Wang, GP Copenhaver - Annual Review of Plant Biology, 2018 - annualreviews.org
Meiosis halves diploid chromosome numbers to haploid levels that are essential for sexual
reproduction in most eukaryotes. Meiotic recombination ensures the formation of bivalents …

Nucleosomes and DNA methylation shape meiotic DSB frequency in Arabidopsis thaliana transposons and gene regulatory regions

K Choi, X Zhao, AJ Tock, C Lambing… - Genome …, 2018 - genome.cshlp.org
Meiotic recombination initiates from DNA double-strand breaks (DSBs) generated by SPO11
topoisomerase-like complexes. Meiotic DSB frequency varies extensively along eukaryotic …

Using next-generation sequencing to isolate mutant genes from forward genetic screens

K Schneeberger - Nature Reviews Genetics, 2014 - nature.com
The long-lasting success of forward genetic screens relies on the simple molecular basis of
the characterized phenotypes, which are typically caused by mutations in single genes …