In tumours, hypoxia—a condition in which the demand for oxygen is higher than its
availability—is well known to be associated with reduced sensitivity to radiotherapy and …

Sarcomas are a rare heterogeneous group of malignant neoplasms of mesenchymal origin
which represent approximately 13% of all cancers in pediatric patients. The most prevalent …

Background Various parameters have been considered for predicting survival in pancreatic
ductal adenocarcinoma. Information about western population is missing. The aim of this …

Purpose To investigate the correlation between DWI, intravoxel incoherent motion (IVIM),
and hypoxia‐inducible factor 1‐alpha (HIF‐1α) expression in a nude mouse model of …

Rhabdomyosarcoma (RMS) is the most common pediatric soft-tissue malignant tumor.
Treatment of RMS usually includes primary tumor resection along with systemic …

Simple Summary Rhabdomyosarcoma is a rare type of childhood cancer. Current treatment
options include surgery, radiotherapy, and chemotherapy. Survival chances for RMS …

Background Activation of immune checkpoints, eg PD-1/PD-L1 axis, in cancer
microenvironment, enables evasion of host anti-cancer immune response and drives tumor …

Malignant peripheral nerve sheath tumor (MPNST) in children is a rare mesenchymal
malignancy developing predominantly in the setting of neurofibromatosis type 1. The …

Rhabdomyosarcoma (RMS) is an aggressive pediatric tumor with a poor prognosis for
metastasis and recurrent disease. Large-scale sequencing endeavors demonstrate that …

Over the last few years, we have seen constant development of molecular pathology for the
care of patients with cancer. The information obtained from molecular data has transformed …