Based on engineered or bacterial nucleases, the development of genome editing
technologies has opened up the possibility of directly targeting and modifying genomic …

This article is part of the Top 10 Unanswered Questions in MPMI invited review series.
Plants recognize the presence or invasion of microbes through cell surface-localized pattern …

Citrus canker, caused by Xanthomonas citri subsp. citri (Xcc), is severely damaging to the
global citrus industry. Targeted editing of host disease‐susceptibility genes represents an …

Xanthomonas oryzae pv. oryzae (Xoo), the causal agent of bacterial blight of rice, employs
the transcription activator-like effectors (TALEs) to induce the expression of the OsSWEET …

Rice (Oryza sativa L.) is a staple food crop, feeding more than 50% of the world's population.
Diseases caused by bacterial, fungal, and viral pathogens constantly threaten the rice …

Genome editing by sequence-specific nucleases (SSNs) has revolutionized biology by
enabling targeted modifications of genomes. Although routine plant genome editing …

Engineered transcription activator–like effector nucleases (TALENs) have shown promise as
facile and broadly applicable genome editing tools. However, no publicly available high …

TALENs are important new tools for genome engineering. Fusions of transcription activator-
like (TAL) effectors of plant pathogenic Xanthomonas spp. to the FokI nuclease, TALENs …

Nucleases that cleave unique genomic sequences in living cells can be used for targeted
gene editing and mutagenesis. Here we develop a strategy for generating such reagents …

Genome editing technology has rapidly evolved to knock-out genes, create targeted genetic
variation, install precise insertion/deletion and single nucleotide changes, and perform large …