Tumor-and circulating-free DNA methylation identifies clinically relevant small cell lung cancer subtypes

S Heeke, CM Gay, MR Estecio, H Tran, BB Morris… - Cancer cell, 2024 - cell.com
Small cell lung cancer (SCLC) is an aggressive malignancy composed of distinct
transcriptional subtypes, but implementing subtyping in the clinic has remained challenging …

Tissue and circulating biomarkers of benefit to immunotherapy in extensive-stage small cell lung cancer patients

M Lorenzi, MV Resi, L Bonanno, S Frega… - Frontiers in …, 2024 - frontiersin.org
Extensive stage-Small-Cell Lung Cancer (ES-SCLC) is an aggressive cancer with dismal
prognosis. The addition of immune-checkpoint inhibitors (ICIs) to platinum-based …