IgA vasculitis update: epidemiology, pathogenesis, and biomarkers

L Xu, Y Li, X Wu - Frontiers in Immunology, 2022 - frontiersin.org
Immunoglobulin A vasculitis (IgAV), formerly known as Henoch-Schönlein purpura, is the
most common systemic vasculitis in children, characterized by diverse clinical …

Pathogenesis of IgA nephropathy

KN Lai - Nature Reviews Nephrology, 2012 - nature.com
Since its first description in 1968, IgA nephropathy has remained the most common form of
idiopathic glomerulonephritis leading to chronic kidney disease in developed countries. The …

Cosmc is an essential chaperone for correct protein O-glycosylation

Y Wang, T Ju, X Ding, B Xia, W Wang… - Proceedings of the …, 2010 - National Acad Sciences
Cosmc is a molecular chaperone thought to be required for expression of active T-synthase,
the only enzyme that galactosylates the Tn antigen (GalNAcα1-Ser/Thr-R) to form core 1 …

Galactosylation of IgA1 is associated with common variation in C1GALT1

DP Gale, K Molyneux, D Wimbury… - Journal of the …, 2017 - journals.lww.com
IgA nephropathy (IgAN), an important cause of kidney failure, is characterized by glomerular
IgA deposition and is associated with changes in O-glycosylation of the IgA1 molecule …

Aberrantly glycosylated IgA1 in IgA nephropathy: What we know and what we don't know

Y Ohyama, MB Renfrow, J Novak… - Journal of Clinical …, 2021 - mdpi.com
IgA nephropathy (IgAN), the most common primary glomerular disease worldwide, is
characterized by glomerular deposition of IgA1-containing immune complexes. The IgA1 …

Genetic studies of IgA nephropathy: past, present, and future

K Kiryluk, BA Julian, RJ Wyatt, F Scolari, H Zhang… - Pediatric …, 2010 - Springer
Immunoglobulin A nephropathy (IgAN) is the most common form of primary
glomerulonephritis worldwide and an important cause of kidney disease in young adults …

Evidence-based clinical practice guidelines for IgA nephropathy 2014

Y Yuzawa, R Yamamoto, K Takahashi… - Clinical and …, 2016 - Springer
Immunoglobulin A (IgA) nephropathy (IgAN) is the most common primary
glomerulonephritis, and patients typically require dialysis when the disease progresses to …

Immunoglobulin A nephropathy: current progress and future directions

C Zhang, X Zeng, Z Li, Z Wang, S Li - Translational Research, 2015 - Elsevier
Immunoglobulin A (IgA) nephropathy is the most prevalent form of primary
glomerulonephritis that often leads to end-stage kidney failure, thereby representing a major …

Genetic determinants of IgA nephropathy: eastern perspective

M Li, XQ Yu - Seminars in Nephrology, 2018 - Elsevier
IgA nephropathy (IgAN) is one of the most common primary glomerulonephritides
throughout the world and a major cause of end-stage renal disease among the East Asian …

Genetics and immunopathogenesis of IgA nephropathy

HH Yu, KH Chu, YH Yang, JH Lee, LC Wang… - Clinical reviews in …, 2011 - Springer
IgA nephropathy (IgAN) is the most common glomerulonephritis in the world. The hallmark of
IgAN is underglycosylation in the hinge region of IgA1. Increasing evidence supports the …