Performance of capecitabine in novel combination therapies in colorectal cancer

FD Pouya, Y Rasmi, IY Camci, Y Tutar… - Journal of …, 2021 - Taylor & Francis
Colorectal cancer is one of the most common cancers throughout the world, and no
definitive cure has ever been found. Perhaps a new insight into the effectiveness of …

Association of single-nucleotide polymorphisms in capecitabine bioactivation pathway with adjuvant therapy safety in colorectal cancer patients

Y Cura, A Sánchez-Martín, N Márquez-Pete… - Pharmaceutics, 2023 - mdpi.com
Capecitabine, an oral prodrug of 5-fluorouracil (5-FU), is part of the standard treatment of
colorectal cancer (CRC). Severe adverse dose limiting reactions that impair treatment safety …

Cost–effectiveness of extended DPYD testing before fluoropyrimidine chemotherapy in metastatic breast cancer in the UK

R Koleva-Kolarova, H Vellekoop, S Huygens… - Personalized …, 2023 - Taylor & Francis
The aim of this study was to evaluate the cost–effectiveness of ToxNav©, a multivariant
genetic test, to screen for DPYD followed by personalized chemotherapy dosing for …

Effect of capecitabine as monotherapy for HER2 normal metastatic breast cancer

ADM Knudsen, MW Modvig, M Vogsen, AR Kodahl - Medical Oncology, 2024 - Springer
This study aimed to evaluate the efficacy of capecitabine monotherapy for patients with
human epidermal growth factor receptor-2 (HER2) normal metastatic breast cancer (MBC) …

A prospective, open-label, multicenter phase IV clinical trial on the safety and efficacy of lobaplatin-based chemotherapy in advanced breast cancer

M Yan, P Yuan, Q Ouyang, Y Cheng… - Therapeutic …, 2022 - journals.sagepub.com
Background: Since lobaplatin (LBP) has been approved to treat metastatic breast cancer in
China, this study aimed to evaluate the safety and efficacy of LBP-based chemotherapy in …

[HTML][HTML] Capecitabine monotherapy as first-line treatment in advanced HER2-normal breast cancer–a nationwide, retrospective study

A Celik, T Berg, M Gibson, MB Jensen… - Acta …, 2024 - pmc.ncbi.nlm.nih.gov
Background and purpose Capecitabine can be used as first-line treatment for advanced
breast cancer. However, real-world data on efficacy of capecitabine in this setting is sparse …

Capecitabine in combination with bendamustine in pretreated women with HER2-negative metastatic breast cancer: results of a phase II trial (AGMT MBC-6)

G Rinnerthaler, SP Gampenrieder… - Therapeutic …, 2021 - journals.sagepub.com
Background: Bendamustine, a medication approved for the treatment of indolent non-
Hodgkin lymphoma, has already shown anticancer activity in metastatic breast cancer …

Association of Single-Nucleotide Polymorphisms in Capecitabine Bioactivation Pathway with Adjuvant Therapy Safety in Colorectal Cancer Patients

YA Cura Cuevas, A Sánchez Martín, N Márquez Pete… - 2023 - digibug.ugr.es
Capecitabine, an oral prodrug of 5-fluorouracil (5-FU), is part of the standard treatment of
colorectal cancer (CRC). Severe adverse dose limiting reactions that impair treatment safety …