Neonatal hypoxic ischemic encephalopathy: an update on disease pathogenesis and treatment

EP Yıldız, B Ekici, B Tatlı - Expert review of neurotherapeutics, 2017 - Taylor & Francis
Introduction: Hypoxic ischemic encephalopathy (HIE) is the most important reason for
morbidity and mortality in term-born infants. Understanding pathophysiology of the brain …

Hypothermia for newborns with hypoxic-ischemic encephalopathy

B Lemyre, V Chau - Paediatrics & child health, 2018 - academic.oup.com
Therapeutic hypothermia is a standard of care for infants≥ 36 weeks gestational age (GA)
with moderate-to-severe hypoxic-ischemic encephalopathy. Because some studies included …

Levetiracetam versus phenobarbital for neonatal seizures: a randomized controlled trial

C Sharpe, GE Reiner, SL Davis, M Nespeca… - …, 2020 - publications.aap.org
METHODS: The study was a multicenter, randomized, blinded, controlled, phase IIb trial
investigating the efficacy and safety of levetiracetam compared with phenobarbital as a first …

Machine learning for the early prediction of infants with electrographic seizures in neonatal hypoxic‐ischemic encephalopathy

AM Pavel, JM O'Toole, J Proietti, V Livingstone… - …, 2023 - Wiley Online Library
Objective To assess if early clinical and electroencephalography (EEG) features predict later
seizure development in infants with hypoxic‐ischemic encephalopathy (HIE). Methods …

Neuromonitoring in neonatal critical care part I: neonatal encephalopathy and neonates with possible seizures

M El-Dib, NS Abend, T Austin, G Boylan, V Chock… - Pediatric …, 2023 - nature.com
The blooming of neonatal neurocritical care over the last decade reflects substantial
advances in neuromonitoring and neuroprotection. The most commonly used brain …

Neonatal seizures—are we there yet?

G Ramantani, B Schmitt, B Plecko, RM Pressler… - …, 2019 - thieme-connect.com
Neonatal seizures are the most prevalent and distinctive sign of neurologic dysfunction in
early life and pose an immense challenge for clinicians. Improvements in neonatal care …

Hypoxic-ischemic encephalopathy and other neonatal encephalopathies

HC Glass - CONTINUUM: Lifelong Learning in Neurology, 2018 - journals.lww.com
PURPOSE OF REVIEW This article puts advances in the field of neurogenetics into context
and provides a quick review of the broad concepts necessary for current practice in …

Convolutional neural networks ensemble model for neonatal seizure detection

MA Tanveer, MJ Khan, H Sajid, N Naseer - Journal of Neuroscience …, 2021 - Elsevier
Background Neonatal seizures are a common occurrence in clinical settings, requiring
immediate attention and detection. Previous studies have proposed using manual feature …

Incidence of neonatal seizures in china based on electroencephalogram monitoring in neonatal neurocritical care units

K Yan, G Cheng, W Zhou, F Xiao, C Zhang… - JAMA Network …, 2023 - jamanetwork.com
Importance Neonatal seizures pose a significant challenge in critical care, and continuous
video electroencephalography (cEEG) monitoring holds promise for early detection of …

Leveraging electronic medical record-embedded standardised electroencephalogram reporting to develop neonatal seizure prediction models: a retrospective cohort …

JL McKee, MC Kaufman, AK Gonzalez… - The Lancet Digital …, 2023 - thelancet.com
Background Accurate prediction of seizures can help to direct resource-intense continuous
electroencephalogram (CEEG) monitoring to neonates at high risk of seizures. We aimed to …