The role of HDAC3 in inflammation: mechanisms and therapeutic implications

N Watson, S Kuppuswamy, WL Ledford… - Frontiers in …, 2024 - frontiersin.org
Histone deacetylases (HDACs) are critical regulators of inflammatory gene expression, and
the efficacy of pan-HDAC inhibitors has been implicated in various disease conditions …

Unraveling immune cell heterogeneity in autoimmune arthritis: insights from single-cell RNA sequencing

S Nakajima, H Tsuchiya, K Fujio - Immunological Medicine, 2024 - Taylor & Francis
Single-cell RNA sequencing (scRNA-seq) has transformed our understanding of immune-
mediated arthritis, which comprises rheumatoid arthritis and spondyloarthritis. This review …

Identification of therapeutic targets and medicines for comorbid Crohn's disease and rheumatoid arthritis: A comprehensive analysis

Q Dong, X Wu, T Mok, G Cai, Z Zha, G She, J Chen - Heliyon, 2024 - cell.com
Abstract Objective The incidence of Crohn's disease (CD) and rheumatoid arthritis (RA) co-
morbidity, as well as the number of individuals affected, is on the rise due to their shared …

Unique transcriptomic profile of peripheral blood monocytes in rheumatoid arthritis-associated interstitial lung disease

JA Poole, A Schwab, GM Thiele, BR England… - …, 2024 - academic.oup.com
Objectives Though interstitial lung disease (ILD) contributes to excess morbidity and
mortality in rheumatoid arthritis (RA), RA-ILD pathogenesis remains incompletely defined …

慢性粒单核细胞白血病合并自身免疫性疾病研究进展.

查蔷, 李建勇, 沈文怡 - Journal of Nanjing Medical …, 2024 - search.ebscohost.com
慢性粒单核细胞白血病(chronic myelomonocytic leukemia, CMML) 是一类以外周血单核细胞
增多及骨髓异常增生为特征的克隆性造血干细胞疾病. CMML 患者常合并自身免疫性疾病 …

Immunoinformatics for the Diagnosis and Monitoring of Autoimmune Diseases

S Gangwar, N Sharma, D Toor - Concepts in Pharmaceutical …, 2024 - Springer
A complicated and diverse set of illnesses known as autoimmune diseases occur when the
immune system attacks healthy cells and tissues, causing tissue damage and chronic …

[PDF][PDF] Exploring the transcriptomic landscape of rheumatoid arthritis using next-generation RNA sequencing

R Chakraborty, B Jana, S Koner, SK Maiti… - INNOSC Theranostics …, 2024 - researchgate.net
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by inflammation
and joint damage. Transcriptomics has been utilized in RA profiling to identify locations that …