Epithelial-to-mesenchymal transition (EMT) determines the most lethal features of cancer,
metastasis formation and chemoresistance, and therefore represents an attractive target in …

Suramin is 100 years old and is still being used to treat the first stage of acute human
sleeping sickness, caused by Trypanosoma brucei rhodesiense. Suramin is a …

Objective To examine the efficacy of pharmacological treatments for restricted and repetitive
behaviors (RRB) in autism spectrum disorders (ASD). Method We searched PubMed …

Psychiatric disorders are debilitating diseases, affecting> 80 million people worldwide.
There are no causal cures for psychiatric disorders and available therapies only treat the …

In recent years, a substantial body of evidence has emerged demonstrating that purine and
pyrimidine synthesis and metabolism play major roles in controlling embryonic and fetal …

Schizophrenia is considered primarily as a cognitive disorder. However, functional
outcomes in schizophrenia are limited by the lack of effective pharmacological and …

The association between maternal immune activation (MIA) during pregnancy and risk for
offspring neuropsychiatric disorders has been increasingly recognized over the past several …

Early diagnosis and treatment for autism spectrum disorder (ASD) pose challenges. The
current diagnostic approach for ASD is mainly clinical assessment of patient behaviors …

Without healing, multicellular life on Earth would not exist. Without healing, one injury
predisposes to another, leading to disability, chronic disease, accelerated aging, and death …

Autism spectrum disorder (ASD) is a complex neurodevelopmental condition caused by
interactions of environmental and genetic factors. Recently we showed that activation of the …