Guidelines for bioinformatics of single-cell sequencing data analysis in Alzheimer's disease: review, recommendation, implementation and application
Alzheimer's disease (AD) is the most common form of dementia, characterized by
progressive cognitive impairment and neurodegeneration. Extensive clinical and genomic …
progressive cognitive impairment and neurodegeneration. Extensive clinical and genomic …
Role of Ca2+/Calmodulin-Dependent Protein Kinase Type II in Mediating Function and Dysfunction at Glutamatergic Synapses
AG Mohanan, S Gunasekaran, RS Jacob… - Frontiers in molecular …, 2022 - frontiersin.org
Glutamatergic synapses harbor abundant amounts of the multifunctional Ca2+/calmodulin-
dependent protein kinase type II (CaMKII). Both in the postsynaptic density as well as in the …
dependent protein kinase type II (CaMKII). Both in the postsynaptic density as well as in the …
Proteomic Analysis of a Rat Streptozotocin Model Shows Dysregulated Biological Pathways Implicated in Alzheimer's Disease
EMG da Silva, JSG Fischer, ILS Souza… - International Journal of …, 2024 - mdpi.com
Alzheimer's Disease (AD) is an age-related neurodegenerative disorder characterized by
progressive memory loss and cognitive impairment, affecting 35 million individuals …
progressive memory loss and cognitive impairment, affecting 35 million individuals …
Epigenetic modifications of DNA and RNA in Alzheimer's disease
Alzheimer's disease (AD) is a complex neurodegenerative disorder and the most common
form of dementia. There are two main types of AD: familial and sporadic. Familial AD is …
form of dementia. There are two main types of AD: familial and sporadic. Familial AD is …
[HTML][HTML] Identification of Riluzole derivatives as novel calmodulin inhibitors with neuroprotective activity by a joint synthesis, biosensor, and computational guided …
M Baltasar-Marchueta, L Llona, M Sara… - Biomedicine & …, 2024 - Elsevier
The development of new molecules for the treatment of calmodulin related cardiovascular or
neurodegenerative diseases is an interesting goal. In this work, we introduce a novel …
neurodegenerative diseases is an interesting goal. In this work, we introduce a novel …
ABCA1 基因多态性R219K 与帕金森症和阿尔兹海默症发病率的相关性研究.
亚拉盖， 梁琨， 陶娜拉， 刘燕 - Progress in Modern …, 2020 - search.ebscohost.com
摘要目的: 探讨与研究三磷酸腺苷结合盒转运体A1 (Adenosine triphosphate (ATP)-binding
cassette transporter A1) 基因多态性R219K 与帕金森症(Parkinson disease, PD) …
cassette transporter A1) 基因多态性R219K 与帕金森症(Parkinson disease, PD) …
Camk2a suppresses denervated muscle atrophy by maintaining the Ca2+ homeostasis in muscle cells
Y Zhang, M Xia, T Zhao, Q Zhang, R Li… - Cellular and Molecular …, 2023 - cellmolbiol.org
Denervated muscle atrophy is a severe neurological complication that significantly impacts
patients' quality of life. Currently, there is a lack of effective treatment methods. This study …
patients' quality of life. Currently, there is a lack of effective treatment methods. This study …
[HTML][HTML] 阿尔茨海默病患者血液中miRNA-3200-3p 生物信息学分析
闫林娜， 张鑫， 王梓炫 - Advances in Clinical Medicine, 2024 - hanspub.org
目的: 通过生物信息学方法, 探讨阿尔茨海默病(AD) 患者血液中差异表达微小RNA (miRNA)
的生物学功能. 方法: 通过基因表达综合数据库(GEO) 获取AD 相关的数据集GSE46579, 筛选AD …
的生物学功能. 方法: 通过基因表达综合数据库(GEO) 获取AD 相关的数据集GSE46579, 筛选AD …
[图书][B] CaMKII Phosphorylation of the Voltage-Gated Sodium Channel Nav1. 6 Regulates Channel Function and Neuronal Excitability
AS Zybura - 2021 - search.proquest.com
Voltage-gated sodium channels (Navs) undergo remarkably complex modes of modulation
to fine tune membrane excitability and neuronal firing properties. In neurons, the isoform …
to fine tune membrane excitability and neuronal firing properties. In neurons, the isoform …
Β-amiloid peptid varlığında nöronal kalsiyum/kalmodulin-bağımlı Protein Kinaz 2 (CaMK-II) değişimlerinin nörodejenerasyon sürecine etkisi
E Istirman - acikbilim.yok.gov.tr
Demansın en yaygın şekli olarak karşımıza çıkan Alzheimer hastalığı (AH) bilişsel fonksiyon
azalmasının görüldüğü ilerleyici bir nörodejenerasyon durumudur. Hafızanın …
azalmasının görüldüğü ilerleyici bir nörodejenerasyon durumudur. Hafızanın …