Macrophages, as highly phenotypic plastic immune cells, play diverse roles in different
pathological conditions. Changing and controlling the phenotypes of macrophages is …

Our laboratory is focused on investigating the supportive role of P53 towards the
maintenance of lung homeostasis. Acute lung injury, acute respiratory distress syndrome …

Tuberculosis (TB) is one of the leading causes of death worldwide, consistently threatening
public health. Conventional tuberculosis treatment requires a long-term treatment regimen …

Streptococcus pneumoniae (also called pneumococcus) is not only a commensal that
frequently colonizes the human upper respiratory tract but also a pathogen that causes …

Our objective is to explore the effect of P53 on the progression of periodontitis by regulating
macrophages differentiation both in vitro and in vivo. Eighteen normal and periodontitis …

The macrophages contribute to host defense against intracellular pathogens such as
mycobacteria. Mycobacteria interact with macrophages altering their polarization state …

Tuberculosis (TB) accounts for disproportionate morbidity and mortality among persons
living with HIV (PLWH). Conventional methods of TB diagnosis, including smear microscopy …

Tumor-associated macrophages (TAMs) are the essential components of the tumor
microenvironment. TAMs originate from blood monocytes and undergo pro-or anti …

The natural history of tuberculosis (TB) is characterized by a large inter-individual outcome
variability after exposure to Mycobacterium tuberculosis. Specifically, some highly exposed …

The role of biofilms in pathogenicity and treatment strategies is often neglected in
mycobacterial infections. In recent years, the emergence of nontuberculous mycobacterial …