Glutamate abnormalities in obsessive compulsive disorder: neurobiology, pathophysiology, and treatment

C Pittenger, MH Bloch, K Williams - Pharmacology & therapeutics, 2011 - Elsevier
Obsessive compulsive disorder is prevalent, disabling, incompletely understood, and often
resistant to current therapies. Established treatments consist of specialized cognitive …

Sex differences, gonadal hormones and the fear extinction network: implications for anxiety disorders

K Lebron-Milad, MR Milad - Biology of mood & anxiety disorders, 2012 - Springer
Convergent data from rodents and human studies have led to the development of models
describing the neural mechanisms of fear extinction. Key components of the now well …

Effectiveness of deep transcranial magnetic stimulation combined with a brief exposure procedure in post-traumatic stress disorder–a pilot study

M Isserles, AY Shalev, Y Roth, T Peri, I Kutz, E Zlotnick… - Brain stimulation, 2013 - Elsevier
BACKGROUND: Post-traumatic stress disorder (PTSD) is a debilitating anxiety disorder
induced by traumatic experiences. To date, psychotherapy and drug treatment achieve only …

Fear extinction and BDNF: translating animal models of PTSD to the clinic

R Andero, KJ Ressler - Genes, Brain and Behavior, 2012 - Wiley Online Library
Brain‐derived neurotrophic factor (BDNF) is the most studied neurotrophin involved in
synaptic plasticity processes that are required for long‐term learning and memory …

[图书][B] The mind within the brain: How we make decisions and how those decisions go wrong

AD Redish - 2013 - books.google.com
In The Mind within the Brain, David Redish brings together cutting edge research in
psychology, robotics, economics, neuroscience, and the new fields of neuroeconomics and …

Helping oxytocin deliver: considerations in the development of oxytocin-based therapeutics for brain disorders

K Macdonald, D Feifel - Frontiers in neuroscience, 2013 - frontiersin.org
Concerns regarding a drought in psychopharmacology have risen from many quarters. From
one perspective, the wellspring of bedrock medications for anxiety disorders, depression …

[PDF][PDF] Trauma-informed care in behavioral health services

ATI Protocol - Rockville, USA: Substance Abuse and Mental Health …, 2014 - refugees.org
The views, opinions, and content expressed herein are the views of the consensus panel
members and do not necessarily reflect the official position of SAMHSA or HHS. No official …

Effects of moderate treadmill exercise and fluoxetine on behavioural and cognitive deficits, hypothalamic-pituitary-adrenal axis dysfunction and alternations in …

S Shafia, AA Vafaei, SA Samaei, AR Bandegi… - … of Learning and …, 2017 - Elsevier
Post-traumatic stress disorder (PTSD) is a condition that develops after an individual has
experienced a major trauma. Currently, selective serotonin reuptake inhibitors (SSRIs) like …

Enhancing endocannabinoid neurotransmission augments the efficacy of extinction training and ameliorates traumatic stress-induced behavioral alterations in rats

M Morena, A Berardi, P Colucci, M Palmery… - …, 2018 - nature.com
Exposure to a traumatic event may result in the development of post-traumatic stress
disorder (PTSD). Endocannabinoids are crucial modulators of the stress response, interfere …

Animal models of fear relapse

TD Goode, S Maren - Ilar Journal, 2014 - academic.oup.com
Whereas fear memories are rapidly acquired and enduring over time, extinction memories
are slow to form and are susceptible to disruption. Consequently, behavioral therapies that …