[HTML][HTML] Linarin, a glycosylated flavonoid, with potential therapeutic attributes: A comprehensive review

J Mottaghipisheh, H Taghrir, A Boveiri Dehsheikh… - Pharmaceuticals, 2021 - mdpi.com
Many flavonoids, as eminent phenolic compounds, have been commercialized and
consumed as dietary supplements due to their incredible human health benefits. In the …

[HTML][HTML] The role of the NLRP3 inflammasome and programmed cell death in acute liver injury

C Yu, P Chen, L Miao, G Di - International Journal of Molecular Sciences, 2023 - mdpi.com
Acute liver injury (ALI) is a globally important public health issue that, when severe, rapidly
progresses to acute liver failure, seriously compromising the life safety of patients. The …

Anti-inflammatory chemical constituents of Flos Chrysanthemi Indici determined by UPLC-MS/MS integrated with network pharmacology

D Tian, Y Yang, M Yu, ZZ Han, M Wei, HW Zhang… - Food & function, 2020 - pubs.rsc.org
Flos Chrysanthemi Indici (FCI), the flower of Chrysanthemum indicum L., is a common
functional food and a well-known traditional Chinese medicine (TCM) for the treatment of …

Linarin ameliorates dextran sulfate sodium-induced colitis in C57BL/6J mice via the improvement of intestinal barrier, suppression of inflammatory responses and …

C Jin, J Liu, R Jin, Y Yao, S He, M Lei, X Peng - Food & Function, 2022 - pubs.rsc.org
Linarin is a natural flavonoid compound found in Chrysanthemum indicum, Mentha species
and other plants with various biological activities. The study aimed to investigate the …

Biochanin A protects lipopolysaccharide/D-galactosamine-induced acute liver injury in mice by activating the Nrf2 pathway and inhibiting NLRP3 inflammasome …

X Liu, T Wang, X Liu, L Cai, J Qi, P Zhang… - International …, 2016 - Elsevier
Biochanin A, an isoflavone existed in red clover and peanuts, has been reported to possess
a wide spectrum of pharmacological activities, such as anti-inflammatory and antioxidant …

Ameliorative effect of supercritical fluid extract of Chrysanthemum indicum Linnén against D-galactose induced brain and liver injury in senescent mice via …

X Zhang, JZ Wu, ZX Lin, QJ Yuan, YC Li… - Journal of …, 2019 - Elsevier
Abstract Ethnopharmacological relevance Chrysanthemum indicum Linne (C. indicum), a
healthy food and folk medicine in China for thousands of years, has been reported to exert …

[HTML][HTML] Inhibiting TLR4 signaling by linarin for preventing inflammatory response in osteoarthritis

W Qi, Y Chen, S Sun, X Xu, J Zhan, Z Yan… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
Osteoarthritis (OA) is one of the most common degenerative diseases, ultimately leading to
long-term joint pain and severe articular malformation. Controlling local chronic …

Linarin improves the dyskinesia recovery in Alzheimer's disease zebrafish by inhibiting the acetylcholinesterase activity

H Pan, J Zhang, Y Wang, K Cui, Y Cao, L Wang, Y Wu - Life sciences, 2019 - Elsevier
Background Due to complex pathogenesis of Alzheimer's disease (AD), currently there is no
effective disease-modifying treatment. Acetylcholinesterase (AChE) has introduced itself as …

[HTML][HTML] The Phenolic Fraction of Mentha haplocalyx and Its Constituent Linarin Ameliorate Inflammatory Response through Inactivation of NF-κB and MAPKs in …

X Chen, S Zhang, Z Xuan, D Ge, X Chen, J Zhang… - Molecules, 2017 - mdpi.com
Mentha haplocalyx has been widely used for its flavoring and medicinal properties and as a
traditional Chinese medicine with its anti-inflammation properties. The present study was …

[HTML][HTML] Kazakh Ziziphora Species as Sources of Bioactive Substances

K Šmejkal, M Malaník, K Zhaparkulova, Z Sakipova… - Molecules, 2016 - mdpi.com
Ziziphora species represent the prototypical example of the Lamiaceae family. The
phytochemicals present in Ziziphora include monoterpenic essential oils, triterpenes and …