Designing scaffolds for corneal regeneration

M Ahearne, J Fernández‐Pérez… - Advanced Functional …, 2020 - Wiley Online Library
Corneal blindness is one of the most common causes of vision loss worldwide, affecting
millions of people. To treat these patients, researchers have been examining different …

Concise review: stem cells for corneal wound healing

M Saghizadeh, AA Kramerov, CN Svendsen… - Stem Cells, 2017 - academic.oup.com
Corneal wound healing is a complex process that occurs in response to various injuries and
commonly used refractive surgery. It is a significant clinical problem, which may lead to …

An injectable, shape-retaining collagen hydrogel cross-linked using thiol-maleimide click chemistry for sealing corneal perforations

J Rosenquist, M Folkesson, L Höglund… - … Applied Materials & …, 2023 - ACS Publications
Injectable hydrogels show great promise in developing novel regenerative medicine
solutions and present advantages for minimally invasive applications. Hydrogels based on …

Simple limbal epithelial transplantation: current status and future perspectives

CJ Jackson, IT Myklebust Ernø… - Stem cells …, 2020 - academic.oup.com
Damage to limbal stem cells as a result of injury or disease can lead to limbal stem cell
deficiency (LSCD). This disease is characterized by decreased vision that is often painful …

Epithelial ingrowth following laser in situ keratomileusis (LASIK): prevalence, risk factors, management and visual outcomes

DSJ Ting, S Srinivasan, JP Danjoux - BMJ open ophthalmology, 2018 - bmjophth.bmj.com
The number of laser in situ keratomileusis (LASIK) procedures is continuing to rise. Since its
first application for correcting simple refractive errors over 25 years ago, the role of LASIK …

The human tissue-engineered cornea (hTEC): Recent Progress

LP Guérin, G Le-Bel, P Desjardins, C Couture… - International Journal of …, 2021 - mdpi.com
Each day, about 2000 US workers have a job-related eye injury requiring medical treatment.
Corneal diseases are the fifth cause of blindness worldwide. Most of these diseases can be …

Native and synthetic scaffolds for limbal epithelial stem cell transplantation

KN Nguyen, S Bobba, A Richardson, M Park… - Acta biomaterialia, 2018 - Elsevier
Limbal stem cell deficiency (LSCD) is a complex blinding disease of the cornea, which
cannot be treated with conventional corneal transplants. Instead, a stem cell (SC) graft is …

Fibrin nanoparticles coupled with keratinocyte growth factor enhance the dermal wound-healing rate

I Muhamed, EP Sproul, FS Ligler… - ACS applied materials & …, 2019 - ACS Publications
Expediting the wound-healing process is critical for patients chronically ill from nonhealing
wounds and diseases such as hemophilia or diabetes or who have suffered trauma …

The chemistry and engineering of mussel-inspired glue matrix for tissue adhesive and hemostatic

PTM Phuong, HJ Won, YJ Oh, HS Lee, KD Lee… - Journal of Industrial and …, 2019 - Elsevier
The present study aimed to develop a bio-adhesive material with excellent hemostatic and
rapid wound healing properties using a catechol moiety (2chloro-3′, 4 …

Rapid soft tissue approximation and repair using laser‐activated silk nanosealants

R Urie, C Guo, D Ghosh, M Thelakkaden… - Advanced functional …, 2018 - Wiley Online Library
Tissue approximation and repair are conventionally performed with sutures and staples, but
these means are inherently traumatic. Tissue approximation using laser‐responsive …