Muscle membrane integrity in Duchenne muscular dystrophy: recent advances in copolymer-based muscle membrane stabilizers
The scientific premise, design, and structure-function analysis of chemical-based muscle
membrane stabilizing block copolymers are reviewed here for applications in striated …
membrane stabilizing block copolymers are reviewed here for applications in striated …
Modeling of nonlinear optical phenomena in host-guest systems using bond fluctuation Monte Carlo model: a review
We review the results of Monte Carlo studies of chosen nonlinear optical effects in host-
guest systems, using methods based on the bond-fluctuation model (BFM) for a polymer …
guest systems, using methods based on the bond-fluctuation model (BFM) for a polymer …
Synthesis and micellization of bottlebrush poloxamers
JF Hassler, NJ Van Zee, AA Crabtree, FS Bates… - ACS macro …, 2022 - ACS Publications
Bottlebrush polymers are characterized by an expansive parameter space, including graft
length and spacing along the backbone, and these features impact various structural and …
length and spacing along the backbone, and these features impact various structural and …
Discovery of Kinetic Trapping of Poloxamers inside Liposomes via Thermal Treatment
JF Hassler, M Lawson, EC Arroyo, FS Bates… - Langmuir, 2023 - ACS Publications
Poloxamers, a class of biocompatible, commercially available amphiphilic block polymers
(ABPs) comprising poly (ethylene oxide)(PEO) and poly (propylene oxide)(PPO) blocks …
(ABPs) comprising poly (ethylene oxide)(PEO) and poly (propylene oxide)(PPO) blocks …
Quantifying binding of ethylene oxide–propylene oxide block copolymers with lipid bilayers
W Zhang, KJ Haman, JM Metzger, BJ Hackel… - Langmuir, 2017 - ACS Publications
Block copolymers composed of poly (ethylene oxide)(PEO) and poly (propylene
oxide)(PPO) have been widely used in cell membrane stabilization and permeabilization. To …
oxide)(PPO) have been widely used in cell membrane stabilization and permeabilization. To …
Concentration Threshold for Membrane Protection by PEO–PPO Block Copolymers with Variable Molecular Architectures
Poloxamer 188, a poly (ethylene oxide)-b-poly (propylene oxide)-b-poly (ethylene
oxide)(PEO–PPO–PEO) triblock copolymer, protects cell membranes in several injury …
oxide)(PEO–PPO–PEO) triblock copolymer, protects cell membranes in several injury …
Effect of bottlebrush poloxamer architecture on binding to liposomes
Poloxamers─ triblock copolymers consisting of poly (ethylene oxide)(PEO) and poly
(propylene oxide)(PPO)─ have demonstrated cell membrane stabilization efficacy against …
(propylene oxide)(PPO)─ have demonstrated cell membrane stabilization efficacy against …
Influence of cholesterol and bilayer curvature on the interaction of PPO–PEO block copolymers with liposomes
Interactions of nonionic poly (ethylene oxide)-b-poly (propylene oxide)(PEO–PPO) block
copolymers, known as Pluronics or poloxamers, with cell membranes have been widely …
copolymers, known as Pluronics or poloxamers, with cell membranes have been widely …
All-atom molecular dynamics-based analysis of membrane-stabilizing copolymer interactions with lipid bilayers probed under constant surface tensions
An all-atom phospholipid bilayer and triblock copolymer model was developed for molecular
dynamics (MD) studies. These were performed to investigate the mechanism of interaction …
dynamics (MD) studies. These were performed to investigate the mechanism of interaction …
PEO–PPO diblock copolymers protect myoblasts from hypo-osmotic stress in vitro dependent on copolymer size, composition, and architecture
Poloxamer 188, a triblock copolymer of poly (ethylene oxide)(PEO) and poly (propylene
oxide)(PPO), protects cellular membranes from various stresses. Though numerous block …
oxide)(PPO), protects cellular membranes from various stresses. Though numerous block …