YERSINIA OUTER PROTEINS: Role in Modulation of Host Cell Signaling Responses and Pathogenesis

GI Viboud, JB Bliska - Annu. Rev. Microbiol., 2005 - annualreviews.org
A type III secretion system (TTSS) is encoded on a virulence plasmid that is common to three
pathogenic Yersinia species: Y. enterocolitica, Y. pseudotuberculosis, and Y. pestis …

Insights into host responses against pathogens from transcriptional profiling

RG Jenner, RA Young - Nature Reviews Microbiology, 2005 - nature.com
DNA microarrays have allowed us to monitor the effects of pathogens on host-cell gene
expression programmes in great depth and on a broad scale. The comparison of results that …

The Yersinia Ysc–Yop 'Type III' weaponry

GR Cornelis - Nature Reviews Molecular Cell Biology, 2002 - nature.com
Abstract'Type III secretion'—the mechanism by which some pathogenic bacteria inject
proteins straight into the cytosol of eukaryotic cells to'anaesthetize'or'enslave'them—was …

[HTML][HTML] Yersinia type III secretion: send in the effectors

GR Cornelis - The Journal of cell biology, 2002 - ncbi.nlm.nih.gov
Abstract Pathogenic Yersinia spp (Yersinia pestis, Yersinia pseudotuberculosis, and
Yersinia enterocolitica) have evolved an exquisite method for delivering powerful effectors …

Pathogenesis of Y. enterocolitica and Y. pseudotuberculosis in Human Yersiniosis

CL Galindo, JA Rosenzweig, ML Kirtley… - Journal of …, 2011 - Wiley Online Library
Yersiniosis is a food‐borne illness that has become more prevalent in recent years due to
human transmission via the fecal‐oral route and prevalence in farm animals. Yersiniosis is …

Interleukin-10 and inhibition of innate immunity to Yersiniae: roles of Yops and LcrV (V antigen)

RR Brubaker - Infection and immunity, 2003 - Am Soc Microbiol
Plague, caused by Yersinia pestis, is recognized as the most devastating acute infectious
disease experienced by humankind. This notoriety is based upon the high rate of mortality …

Leptospirosis: pathogenesis, immunity, and diagnosis

RUM Palaniappan, S Ramanujam… - Current opinion in …, 2007 - journals.lww.com
Leptospirosis: pathogenesis, immunity, and diagnosis : Current Opinion in Infectious
Diseases Leptospirosis: pathogenesis, immunity, and diagnosis : Current Opinion in …

The Yersinia virulence factor YopM forms a novel protein complex with two cellular kinases

C McDonald, PO Vacratsis, JB Bliska… - Journal of Biological …, 2003 - ASBMB
Pathogenic Yersinia contain a virulence plasmid that encodes genes for intracellular
effectors, which neutralize the host immune response. One effector, YopM, is necessary for …

Yersinia outer proteins: Yops

JE Trosky, ADB Liverman, K Orth - Cellular microbiology, 2008 - Wiley Online Library
The pathogenic bacteria Yersinia spp. contain a virulence plasmid that encodes a type III
secretion system and effectors. During infection, four of the effectors target the actin …

Targeting Rac1 by the Yersinia effector protein YopE inhibits caspase-1-mediated maturation and release of interleukin-1β

P Schotte, G Denecker, A Van Den Broeke… - Journal of Biological …, 2004 - ASBMB
Yersinia bacteria can take control of the host cell by injecting so-called Yop effector proteins
into the cytosol of the cells to which they adhere. Using Yersinia enterocolitica strains that …