Grape (Vitis vinifera L.) phytochemicals and their biochemical protective mechanisms against leading pathologies

U Majeed, A Shafi, H Majeed, K Akram, X Liu, J Ye… - Food Chemistry, 2023 - Elsevier
The intake of herbal dietary constituents, mostly fruits and vegetables, have been
considered well-known to prevent pathologies (degenerative diseases). Consumer …

Impact of the inhibition of proteins activities and the chemical aspect of polyphenols-proteins interactions

NS Adrar, K Madani, S Adrar - PharmaNutrition, 2019 - Elsevier
The good nutritional value and the interesting biological activities of the plant-based
nutraceuticals are primarily due to the polyphenols. These latter are among the most …

The efficacy of berries against lipopolysaccharide-induced inflammation: A review

M Gasparrini, TY Forbes-Hernandez… - Trends in Food Science …, 2021 - Elsevier
Background an increasing number of epidemiological studies highlights a remarkable
association between a diet rich in fruits and vegetables and a lower incidence of different …

Ghrelin protects against contact dermatitis and psoriasiform skin inflammation by antagonizing TNF-α/NF-κB signaling pathways

R Qu, X Chen, J Hu, Y Fu, J Peng, Y Li, J Chen, P Li… - Scientific Reports, 2019 - nature.com
Contact dermatitis and psoriasis are skin disorders caused by immune dysregulation, yet
much remains unknown about their underlying mechanisms. Ghrelin, a recently discovered …

[HTML][HTML] Bioactive compounds from dietary whole grape seed meal improved colonic inflammation via inhibition of MAPKs and NF-kB signaling in pigs with DSS …

GC Pistol, DE Marin, MC Rotar, M Ropota… - Journal of functional …, 2020 - Elsevier
Abstract The management of Inflammatory Bowel Diseases symptoms is focused to find new
alternative strategies which could have beneficial effects on intestinal inflammation including …

BRD4 promotes tumor progression and NF-κB/CCL2-dependent tumor-associated macrophage recruitment in GIST

J Mu, P Sun, Z Ma, P Sun - Cell death & disease, 2019 - nature.com
The most commonly occurring sarcoma of the soft tissue is gastrointestinal stromal tumor
(GIST). Treatment and prevention of the disease necessitate an understanding of the …

Optimized extraction by response surface methodology used for the characterization and quantification of phenolic compounds in whole red grapes (Vitis vinifera)

L Iglesias-Carres, A Mas-Capdevila, L Sancho-Pardo… - Nutrients, 2018 - mdpi.com
Scientific research has focused on the characterization of bioactive polyphenols from grape
seeds and skins, and the pulp has often been overlooked. However, since the beneficial …

LncRNA FIRRE/NF-kB feedback loop contributes to OGD/R injury of cerebral microglial cells

Y Zang, X Zhou, Q Wang, X Li, H Huang - Biochemical and biophysical …, 2018 - Elsevier
Stroke is one of the leading causes for serious long-term neurological disability. LncRNAs
have been investigated to be dysregulated in ischemic stroke. However, the underlying …

[HTML][HTML] Whole and polysaccharide powdered Sporisorium reilianum improves DSS-induced colitis in BALB/c mice by modulating gut microbiota

X Yang, S Li, C Wang, Y Lou, X Xia, H Xu - Journal of Functional Foods, 2021 - Elsevier
This study aimed to evaluate whether the whole powder (SRPW) and polysaccharide
(SRPS) from Sporisorium reilianum could modulate the gut microbiota in mice with dextran …

Impacts of regular consumption of grapes on macular pigment accumulation in Singapore older adults: a randomized controlled trial

W Hu, R Zheng, Y Feng, D Tan, GC Chung-Tsing… - Food & Function, 2023 - pubs.rsc.org
Background: Oxidative stress is a key risk factor for visual impairment and consuming dietary
antioxidant-rich foods may help in managing visual impairments. However, a limited number …