The vast increase in Alzheimer disease (AD) worldwide has grave implications for
individuals, family support systems and the health-care systems that will attempt to cope with …

Background The literature regarding clinical olfaction, olfactory loss, and olfactory
dysfunction has expanded rapidly over the past two decades, with an exponential rise in the …

Abstract Purpose of Review The sense of smell is today one of the focuses of interest in
aging and neurodegenerative disease research. In several neurodegenerative diseases …

Aging is associated with alterations in cognitive processing and brain neurophysiology.
Whereas the primary symptom of amnestic mild cognitive impairment (aMCI) is memory …

Objective To evaluate the safety and efficacy of low-dose naproxen for prevention of
progression in presymptomatic Alzheimer disease (AD) among cognitively intact persons at …

Alzheimer's and Parkinson's diseases are the most prevalent neurodegenerative disorders.
Their etiologies are idiopathic, and treatments are symptomatic and orientated towards …

Background: Poor olfaction is common among older adults and has been linked to higher
mortality. However, most studies have had a relatively short follow-up and have not explored …

Animals must discern important stimuli and place them onto their cognitive map of their
environment. The neocortex conveys general representations of sensory events to the …

Cerebrospinal fluid (CSF) flows through the brain, transporting chemical signals and
removing waste. CSF production in the brain is balanced by a constant outflow of CSF, the …

Alzheimer's disease (AD) is a progressive degenerative neurological disorder affecting
nearly one in nine elderly people in the United States. Population studies have shown that …