Succinate dehydrogenase inhibitors (SDHi) are fungicides used to control the proliferation of
pathogenic fungi in crops. Their mode of action is based on blocking the activity of succinate …

After decades of research, our knowledge of the complexity of cancer mechanisms,
elegantly summarized as 'hallmarks of cancer', is expanding, as are the therapeutic …

The multi-factorial Parkinson's disease (PD) is known to be associated with mitochondrial
dysfunction, endoplasmic reticulum stress, alpha synuclein aggregation and dopaminergic …

Accumulating evidence indicates that mitochondria play crucial roles in immunity. However,
the role of the mitochondrial Krebs cycle in immunity remains largely unknown, in particular …

Pheochromocytoma (PHEO) and paraganglioma (PGL)(together PPGL) are tumors with
poor outcomes that arise from neuroendocrine cells in the adrenal gland, and sympathetic …

The 24B_1 small non-coding RNA molecule has been identified in Escherichia coli after
induction of Shiga toxin-converting bacteriophage Φ24B. In this work, we focused on its …

This study aimed to investigate the effects of cisplatin on adenosine triphosphate (ATP)
levels, expressions of genes related to mitochondrial oxidative phosphorylation (OXPHOS) …

Mitochondrial Complex II is composed of four core subunits and mutations to any of the
subunits result in lowered Complex II activity. Surprisingly, although mutations in any of the …

Malignant middle ear paraganglioma (MEPGL) is an exceedingly rare tumor of the
neuroendocrine system. In general, MEPGLs represent as slow growing and …

We investigated the hypothesis that tumourigenesis in SDHB mutant paraganglioma
involves aberrant neurogenic development by comparing differentially expressed gene lists …