[HTML][HTML] Rationale for the use of N‐acetylcysteine in both prevention and adjuvant therapy of COVID‐19
S De Flora, R Balansky, S La Maestra - The FASEB journal, 2020 - ncbi.nlm.nih.gov
COVID‐19 may cause pneumonia, acute respiratory distress syndrome, cardiovascular
alterations, and multiple organ failure, which have been ascribed to a cytokine storm, a …
alterations, and multiple organ failure, which have been ascribed to a cytokine storm, a …
[HTML][HTML] Cellular and molecular signatures of oxidative stress in bronchial epithelial cell models injured by cigarette smoke extract
Exposure of the airways epithelium to environmental insults, including cigarette smoke,
results in increased oxidative stress due to unbalance between oxidants and antioxidants in …
results in increased oxidative stress due to unbalance between oxidants and antioxidants in …
Cigarette smoke extract induces ferroptosis in vascular smooth muscle cells
A Sampilvanjil, T Karasawa… - American Journal …, 2020 - journals.physiology.org
Cigarette smoking is a major risk factor for aortic aneurysm and dissection; however, no
causative link between smoking and these aortic disorders has been proven. In the present …
causative link between smoking and these aortic disorders has been proven. In the present …
[HTML][HTML] Attenuation of cigarette-smoke-induced oxidative stress, senescence, and inflammation by berberine-loaded liquid crystalline nanoparticles: in vitro study in …
Cigarette smoke is considered a primary risk factor for chronic obstructive pulmonary
disease. Numerous toxicants present in cigarette smoke are known to induce oxidative …
disease. Numerous toxicants present in cigarette smoke are known to induce oxidative …
[HTML][HTML] Antioxidants and COVID-19
S DE FLORA, R Balansky… - Journal of preventive …, 2021 - ncbi.nlm.nih.gov
Oxidative mechanisms are not only involved in chronic degenerative diseases but also in
infectious diseases, among which viral respiratory diseases. Antioxidants have the capability …
infectious diseases, among which viral respiratory diseases. Antioxidants have the capability …
Nicotine promotes e-cigarette vapour-induced lung inflammation and structural alterations
ET Roxlau, O Pak, S Hadzic… - European …, 2023 - Eur Respiratory Soc
Background Electronic cigarette (e-cigarette) vapour is gaining popularity as an alternative
to tobacco smoking and can induce acute lung injury. However, the specific role of nicotine …
to tobacco smoking and can induce acute lung injury. However, the specific role of nicotine …
[HTML][HTML] Zerumbone liquid crystalline nanoparticles protect against oxidative stress, inflammation and senescence induced by cigarette smoke extract in vitro
The purpose of this study was to evaluate the potential of zerumbone-loaded liquid
crystalline nanoparticles (ZER-LCNs) in the protection of broncho-epithelial cells and …
crystalline nanoparticles (ZER-LCNs) in the protection of broncho-epithelial cells and …
[HTML][HTML] The link between type 2 diabetes mellitus and the polymorphisms of glutathione-metabolizing genes suggests a new hypothesis explaining disease initiation …
I Azarova, E Klyosova, A Polonikov - Life, 2021 - mdpi.com
The present study investigated whether type 2 diabetes (T2D) is associated with
polymorphisms of genes encoding glutathione-metabolizing enzymes such as glutathione …
polymorphisms of genes encoding glutathione-metabolizing enzymes such as glutathione …
[HTML][HTML] The impact of genetic polymorphisms in glutamate-cysteine ligase, a key enzyme of glutathione biosynthesis, on ischemic stroke risk and brain infarct size
A Polonikov, I Bocharova, I Azarova, E Klyosova… - Life, 2022 - mdpi.com
The purpose of this pilot study was to explore whether polymorphisms in genes encoding
the catalytic (GCLC) and modifier (GCLM) subunits of glutamate-cysteine ligase, a rate …
the catalytic (GCLC) and modifier (GCLM) subunits of glutamate-cysteine ligase, a rate …
[HTML][HTML] Clinical efficacy of carbocysteine in COPD: beyond the mucolytic action
E Pace, I Cerveri, D Lacedonia, G Paone… - Pharmaceutics, 2022 - mdpi.com
Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease with a versatile
and complicated profile, being the fourth most common single cause of death worldwide …
and complicated profile, being the fourth most common single cause of death worldwide …