AIDS as a zoonosis: scientific and public health implications

BH Hahn, GM Shaw, KM De, Cock, PM Sharp - Science, 2000 - science.org
Evidence of simian immunodeficiency virus (SIV) infection has been reported for 26 different
species of African nonhuman primates. Two of these viruses, SIVcpz from chimpanzees and …

Pathogenesis of human immunodeficiency virus infection

JA Levy - Microbiological reviews, 1993 - Am Soc Microbiol
The lentivirus human immunodeficiency virus (HIV) causes AIDS by interacting with a large
number of different cells in the body and escaping the host immune response against it. HIV …

Origin of HIV-1 in the chimpanzee Pan troglodytes troglodytes

F Gao, E Bailes, DL Robertson, Y Chen… - Nature, 1999 - nature.com
The human AIDS viruses human immunodeficiency virus type 1 (HIV-1) and type 2 (HIV-2)
represent cross-species (zoonotic) infections,,,. Although the primate reservoir of HIV-2 has …

Timing the ancestor of the HIV-1 pandemic strains

B Korber, M Muldoon, J Theiler, F Gao, R Gupta… - science, 2000 - science.org
HIV-1 sequences were analyzed to estimate the timing of the ancestral sequence of the
main group of HIV-1, the strains responsible for the AIDS pandemic. Using parallel …

The evolution of HIV-1 and the origin of AIDS

PM Sharp, BH Hahn - … of the Royal Society B: Biological …, 2010 - royalsocietypublishing.org
The major cause of acquired immune deficiency syndrome (AIDS) is human
immunodeficiency virus type 1 (HIV-1). We have been using evolutionary comparisons to …

Identification of a new human immunodeficiency virus type 1 distinct from group M and group O

F Simon, P Mauclère, P Roques, I Loussert-Ajaka… - Nature medicine, 1998 - nature.com
A highly divergent HIV-1 isolate, designated YBF 30, was obtained in 1995 from a 40-year-
old Cameroonian woman with AIDS. Depending on the genes studied, phylogenetic …

[HTML][HTML] Risk to human health from a plethora of simian immunodeficiency viruses in primate bushmeat

M Peeters, V Courgnaud, B Abela, P Auzel… - Emerging infectious …, 2002 - ncbi.nlm.nih.gov
To assess human exposure to Simian immunodeficiency virus (SIV) in west central Africa,
we looked for SIV infection in 788 monkeys that were hunted in the rainforests of Cameroon …

The origins of acquired immune deficiency syndrome viruses: where and when?

PM Sharp, E Bailes, RR Chaudhuri… - … of the Royal …, 2001 - royalsocietypublishing.org
In the absence of direct epidemiological evidence, molecular evolutionary studies of primate
lentiviruses provide the most definitive information about the origins of human …

Genetic diversity of human immunodeficiency virus type 2: evidence for distinct sequence subtypes with differences in virus biology

F Gao, L Yue, DL Robertson, SC Hill, H Hui… - Journal of …, 1994 - Am Soc Microbiol
The virulence properties of human immunodeficiency virus type 2 (HIV-2) are known to vary
significantly and to range from relative attenuation in certain individuals to high-level …

Recombination in AIDS viruses

DL Robertson, BH Hahn, PM Sharp - Journal of molecular evolution, 1995 - Springer
Recombination contributes to the generation of genetic diversity in human
immunodeficiency viruses (HIV) but can only occur between viruses replicating within the …